ID R4XCJ9_TAPDE Unreviewed; 948 AA.
AC R4XCJ9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Protein HIR {ECO:0000256|RuleBase:RU364014};
GN ORFNames=TAPDE_003933 {ECO:0000313|EMBL:CCG83614.1};
OS Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563
OS / JCM 9778 / NBRC 8474) (Peach leaf curl fungus) (Lalaria deformans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC Taphrinales; Taphrinaceae; Taphrina.
OX NCBI_TaxID=1097556 {ECO:0000313|EMBL:CCG83614.1, ECO:0000313|Proteomes:UP000013776};
RN [1] {ECO:0000313|EMBL:CCG83614.1, ECO:0000313|Proteomes:UP000013776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 /
RC NBRC 8474 {ECO:0000313|Proteomes:UP000013776};
RX PubMed=23631913; DOI=10.1128/mBio.00055-13;
RA Cisse O.H., Almeida J.M.G.C.F., Fonseca A., Kumar A.A., Salojaervi J.,
RA Overmyer K., Hauser P.M., Pagni M.;
RT "Genome sequencing of the plant pathogen Taphrina deformans, the causal
RT agent of peach leaf curl.";
RL MBio 4:e00055-e00013(2013).
CC -!- FUNCTION: Required for replication-independent chromatin assembly and
CC for the periodic repression of histone gene transcription during the
CC cell cycle. {ECO:0000256|ARBA:ARBA00002677,
CC ECO:0000256|RuleBase:RU364014}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364014}.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family.
CC {ECO:0000256|ARBA:ARBA00007306, ECO:0000256|RuleBase:RU364014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCG83614.1}.
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DR EMBL; CAHR02000162; CCG83614.1; -; Genomic_DNA.
DR AlphaFoldDB; R4XCJ9; -.
DR STRING; 1097556.R4XCJ9; -.
DR VEuPathDB; FungiDB:TAPDE_003933; -.
DR eggNOG; KOG0973; Eukaryota.
DR Proteomes; UP000013776; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR031120; HIR1-like.
DR InterPro; IPR011494; HIRA-like_C.
DR InterPro; IPR019015; HIRA_B_motif.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13831; MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; 1.
DR PANTHER; PTHR13831:SF0; PROTEIN HIRA; 1.
DR Pfam; PF07569; Hira; 1.
DR Pfam; PF09453; HIRA_B; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU364014}; Nucleus {ECO:0000256|RuleBase:RU364014};
KW Reference proteome {ECO:0000313|Proteomes:UP000013776};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364014};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|RuleBase:RU364014};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364014};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364014};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 14..47
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 112..144
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 154..185
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 667..885
FT /note="Protein HIRA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07569"
FT REGION 420..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 103492 MW; 601807ECC7397251 CRC64;
MLLLRPSWLG HFAENETRQA IYSLDVSSDG VRLVSGGLDG KVRIWDVAKC LAPPEEVEQS
GLLATMPAHT GTSGSDDKLL IIWEREEGAS VQKRSYGEQE EVKEVWKVHR RLVGHQGDIM
DLAWSHDSAL LVSTGVDSTV FVWSGTTFEK KKEITAHASS VKGITFDPAG KYFATASDDR
TIKVWRTSDL LCEAIISGPF ENSPISTYFR RPSWSPDGNN IAAANSMNGL VPAISIINRG
TWESDINLIG HEGAVEVVKF NPVIFTRDDV QITIVACAGL DRVLSIWNTV QTRPIATSSD
IAEQGISDLA WTPNGLGLFV CSFDGTLTVL RFEEHEFGKA LGRDANEEAL SKYGAGRHGA
VMPESIEQLQ LEDASRKETE ENRKGRIADL MGDVEVHVNG SKNLAPGGET QIRPQQTLDQ
EMHEANQKPG NSSNSVTAQE RTTSIIDNSV PEPAVMPETT SAETGTIPDT PVAAATPKPY
VQKVTMVNGK KRIQPQLISS GPSQPQVLSR PTATTTTPSQ TLDISQPSQA LPRGGIPSLI
IGNKRPAEEE HEDATATKRA TNGASAEIPE FMRPAVVAPA TTVSQIRLGT PQVKSYVSHN
QATGRPYVIE ACNAANSHDP AKITFMRGTR IEWVDYLRSA VVLLIGTASF VAAACEDGGV
IVWTPSGRRY MSQIVLEAIP VFLEARDDYL MVISSVGILH VWNLKQQRSP FAPVSLAPAL
DAASSIVDKI RRTSSVTQAS ITSKGVPIVT LSNGDGFIYH ADMQTWLKVS EGWWAISSSY
WDASGLVSRN GLPPGIIDLV ERRTNDEVMR QGKGRVFSRV VKQALMKEGF ENLETIVSIG
HLENRLAAAK MLDSKDEYHT VVLMYAQKLA EEGMTLRVEE LCRELIGPMT KEIPPSSAWI
PSVLGLDKRD LLRECLVQMG RFRGVQRVCT EFAAILKRVT DSADEIPL
//
