ID R4YPD8_OLEAN Unreviewed; 811 AA.
AC R4YPD8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=imp {ECO:0000313|EMBL:CCK75083.1};
GN Synonyms=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=OLEAN_C09070 {ECO:0000313|EMBL:CCK75083.1};
OS Oleispira antarctica RB-8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Oleispira.
OX NCBI_TaxID=698738 {ECO:0000313|EMBL:CCK75083.1, ECO:0000313|Proteomes:UP000032749};
RN [1] {ECO:0000313|EMBL:CCK75083.1, ECO:0000313|Proteomes:UP000032749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23877221; DOI=10.1038/ncomms3156;
RA Kube M., Chernikova T.N., Al-Ramahi Y., Beloqui A., Lopez-Cortez N.,
RA Guazzaroni M.E., Heipieper H.J., Klages S., Kotsyurbenko O.R., Langer I.,
RA Nechitaylo T.Y., Lunsdorf H., Fernandez M., Juarez S., Ciordia S.,
RA Singer A., Kagan O., Egorova O., Petit P.A., Stogios P., Kim Y.,
RA Tchigvintsev A., Flick R., Denaro R., Genovese M., Albar J.P., Reva O.N.,
RA Martinez-Gomariz M., Tran H., Ferrer M., Savchenko A., Yakunin A.F.,
RA Yakimov M.M., Golyshina O.V., Reinhardt R., Golyshin P.N.;
RT "Genome sequence and functional genomic analysis of the oil-degrading
RT bacterium Oleispira antarctica.";
RL Nat. Commun. 4:2156-2156(2013).
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
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DR EMBL; FO203512; CCK75083.1; -; Genomic_DNA.
DR AlphaFoldDB; R4YPD8; -.
DR STRING; 698738.OLEAN_C09070; -.
DR KEGG; oai:OLEAN_C09070; -.
DR PATRIC; fig|698738.3.peg.947; -.
DR HOGENOM; CLU_009039_0_0_6; -.
DR OrthoDB; 9760225at2; -.
DR Proteomes; UP000032749; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000032749};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 23..811
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5009019557"
FT DOMAIN 73..208
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 324..709
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 811 AA; 92931 MW; 578FE7C49282B221 CRC64;
MNKVFSLLIA IFSTFSTPFA NANEGSEDYA FRPLSWYPLD ELTSAEAEAL PEFCSGKYRP
VAITPRNNTS ILIEADESIA DKNGDAVFKG NVEFHQQDKK IISDQATWSQ TQRSATFTGN
VSIITPELVM SGDSAVINDS AQAEQKNAQV KHSEYSLPNA HMRGTAGTIN SQGESFIQLI
DSTYTFCEPG HNDWDIKASE INLDRESGIG SAWHTQLRIK EVPIMYLPYY RFPIDDRRMT
GFLDPTFTIN GEIQASEMSV PFYLNLHPQV DATITPKEIL DHGLLWQGQV RHLTSIFGYG
ELNYSELKND RSYLQEDGDT PRQDRWLINY QQRGDINENW HHRWVYNEIS DNDYINDTKS
SLGINRETHM PTRGEIYFDK SSWHFNVLGE SYQTVDDTIA LADRPYKRLP QLNLNFVPDS
FSGLTGSMKS QATQFKRDND KLTGTSAING TRLVLDSSVS YTFEWPFAYI TPKADYNIRQ
YQLQDVEQSL IDSGYDENPS VAIPKYSVDA GLFFERELEA FDSGYIQTLE PRIMHLQVPY
YDQSDIPNFD SSALTFNASQ LFRDYRFNGN DRIGDANHTT LGLTTRFLKD SNGTETFNAS
IGRIYYHEDR RVQLSSSTVS EVDSRKKSSD IIESTWNPYD QWRLYSMIEY GEAPKVVGED
SEHDILQKQF SIEYNDKLNH MANISLRENT SESIRQLDLG VFWALNDSWA LIGSRKKDLW
NYDSSDVKPV DPIIEALAGF EYQSCCWRAQ VLYQEQSKRL TDDEDSADKT YSWLLRIELK
GFASFGANPD DIMNQSIRGY STRRYFDFES E
//
