ID R4YVR7_9ACTN Unreviewed; 392 AA.
AC R4YVR7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=UBA/THIF-type NAD/FAD binding protein {ECO:0000313|EMBL:CCM61878.1};
GN ORFNames=BN381_10109 {ECO:0000313|EMBL:CCM61878.1};
OS Candidatus Microthrix parvicella RN1.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Microthrixaceae; Microthrix.
OX NCBI_TaxID=1229780 {ECO:0000313|EMBL:CCM61878.1, ECO:0000313|Proteomes:UP000018291};
RN [1] {ECO:0000313|EMBL:CCM61878.1, ECO:0000313|Proteomes:UP000018291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN1 {ECO:0000313|EMBL:CCM61878.1,
RC ECO:0000313|Proteomes:UP000018291};
RX PubMed=23446830; DOI=10.1038/ismej.2013.6;
RA Jon McIlroy S., Kristiansen R., Albertsen M., Michael Karst S.,
RA Rossetti S., Lund Nielsen J., Tandoi V., James Seviour R., Nielsen P.H.;
RT "Metabolic model for the filamentous 'Candidatus Microthrix parvicella'
RT based on genomic and metagenomic analyses.";
RL ISME J. 7:1161-1172(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCM61878.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CANL01000001; CCM61878.1; -; Genomic_DNA.
DR RefSeq; WP_012222739.1; NZ_HG422565.1.
DR AlphaFoldDB; R4YVR7; -.
DR STRING; 1229780.BN381_10109; -.
DR GeneID; 78311488; -.
DR eggNOG; COG0476; Bacteria.
DR eggNOG; COG0607; Bacteria.
DR HOGENOM; CLU_013325_2_0_11; -.
DR OrthoDB; 9804286at2; -.
DR Proteomes; UP000018291; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00158; RHOD; 1.
DR CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF102; ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF00899; ThiF; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018291};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 27..117
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 392 AA; 42864 MW; F520610EEFDFBF08 CRC64;
MANFRELLTA TKQEIREVDT ETADRLRNEG SLILDVREAD EFETGAVPGA LFIPRGHLES
QIEMKLPNKD TPVIVQCAGG VRSAFAAKTL EQLGYTDVTS MAGGFGKWKD EGRDWKVPQS
LQPDQKNRYK RHLLLPEVGE EGQMKLLDAK VLLLGAGGLG SPSGLYLAAA GVGTIGIVDM
DVVDESNLQR QILHTLDRVG MRKVDSARVA IESLNPDVKV ITHDVRLDAN NIADIISGYD
LVVDGADNFP VRYMLNDASV KLGIPVIHGS IFRFEGNVTV FDPRRGPTYR DLLPEPPPPE
MAPSCAEAGV LGVLPGIVGC IQAIETIKYL LDLGDPLIGR YLAFDALDMT FREFKIRPDP
ANQITWENRD QIQVVELTDQ CMPAPLEAPA AA
//
