ID R4YXD0_9ACTN Unreviewed; 238 AA.
AC R4YXD0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Alanine racemase N-terminal domain-containing protein {ECO:0000259|Pfam:PF01168};
GN ORFNames=BN381_140003 {ECO:0000313|EMBL:CCM62838.1};
OS Candidatus Microthrix parvicella RN1.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Microthrixaceae; Microthrix.
OX NCBI_TaxID=1229780 {ECO:0000313|EMBL:CCM62838.1, ECO:0000313|Proteomes:UP000018291};
RN [1] {ECO:0000313|EMBL:CCM62838.1, ECO:0000313|Proteomes:UP000018291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN1 {ECO:0000313|EMBL:CCM62838.1,
RC ECO:0000313|Proteomes:UP000018291};
RX PubMed=23446830; DOI=10.1038/ismej.2013.6;
RA Jon McIlroy S., Kristiansen R., Albertsen M., Michael Karst S.,
RA Rossetti S., Lund Nielsen J., Tandoi V., James Seviour R., Nielsen P.H.;
RT "Metabolic model for the filamentous 'Candidatus Microthrix parvicella'
RT based on genomic and metagenomic analyses.";
RL ISME J. 7:1161-1172(2013).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|PIRSR:PIRSR004848-1};
CC -!- SIMILARITY: Belongs to the pyridoxal phosphate-binding protein
CC YggS/PROSC family. {ECO:0000256|RuleBase:RU004514}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCM62838.1}.
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DR EMBL; CANL01000006; CCM62838.1; -; Genomic_DNA.
DR RefSeq; WP_012224639.1; NZ_HG422565.1.
DR AlphaFoldDB; R4YXD0; -.
DR STRING; 1229780.BN381_140003; -.
DR GeneID; 78313239; -.
DR eggNOG; COG0325; Bacteria.
DR HOGENOM; CLU_059988_0_1_11; -.
DR OrthoDB; 9804072at2; -.
DR Proteomes; UP000018291; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR InterPro; IPR011078; PyrdxlP_homeostasis.
DR NCBIfam; TIGR00044; YggS family pyridoxal phosphate-dependent enzyme; 1.
DR PANTHER; PTHR10146; PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN; 1.
DR PANTHER; PTHR10146:SF14; PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PIRSF; PIRSF004848; YBL036c_PLPDEIII; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS01211; UPF0001; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR004848-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018291}.
FT DOMAIN 30..228
FT /note="Alanine racemase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01168"
FT MOD_RES 46
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR004848-1"
SQ SEQUENCE 238 AA; 25122 MW; 8478637CC621256C CRC64;
MNELANVSPP PDVRVLSEQI AERSALVRER LDRTAGREVR VVAVSKSHPP STAWAAALAG
HREFGENYAQ ELVGKAGFLA ERGIEVRWHM IGPVQSNKVK VLAPVLGWWH TIDRSKLVRT
IARWSPEGTV MIQRNLSGDP NKAGCTADEV EPLVAEATEA GLDVVGLMGV ATEGSPQLAA
AEFASLVAQA DALALRERCI GMSGDLDVAL AAGATTVRLG SMLFGSRPGS ANGGPSRA
//
