ID R4Z0T1_9ACTN Unreviewed; 406 AA.
AC R4Z0T1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Putative membrane protein {ECO:0000313|EMBL:CCM64275.1};
GN ORFNames=BN381_350135 {ECO:0000313|EMBL:CCM64275.1};
OS Candidatus Microthrix parvicella RN1.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Microthrixaceae; Microthrix.
OX NCBI_TaxID=1229780 {ECO:0000313|EMBL:CCM64275.1, ECO:0000313|Proteomes:UP000018291};
RN [1] {ECO:0000313|EMBL:CCM64275.1, ECO:0000313|Proteomes:UP000018291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN1 {ECO:0000313|EMBL:CCM64275.1,
RC ECO:0000313|Proteomes:UP000018291};
RX PubMed=23446830; DOI=10.1038/ismej.2013.6;
RA Jon McIlroy S., Kristiansen R., Albertsen M., Michael Karst S.,
RA Rossetti S., Lund Nielsen J., Tandoi V., James Seviour R., Nielsen P.H.;
RT "Metabolic model for the filamentous 'Candidatus Microthrix parvicella'
RT based on genomic and metagenomic analyses.";
RL ISME J. 7:1161-1172(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCM64275.1}.
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DR EMBL; CANL01000029; CCM64275.1; -; Genomic_DNA.
DR RefSeq; WP_012228073.1; NZ_HG422565.1.
DR AlphaFoldDB; R4Z0T1; -.
DR STRING; 1229780.BN381_350135; -.
DR GeneID; 78314224; -.
DR eggNOG; COG0628; Bacteria.
DR HOGENOM; CLU_031275_3_2_11; -.
DR Proteomes; UP000018291; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018291};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 26..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 361..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 42313 MW; 63ADAF66C7808689 CRC64;
MDKGTTQPIE SEDERLTPRW LRRSSAWAWQ LGLLLLGMIA VYWLVTHFLV VTLPLMTVAV
LSTLTIPPRD ALVRRGMKPS IAASIVVLGS IAVLMLGVAA LAPSFANQLG DLGPKMEDGY
ESVLDWVESG PIGYDRDELK DFGSRLGDSL SSGNTGVVES VVKGASTAFE FFAGLALLVV
VLFFVTKDSE DLMAWADDRL PGSYRSTATA LGSRAWTALS GYVRGTATIA LIDALGIGLA
LLVLGVPLVI PLTMLVFLGG FLPVIGATVA GLVAVLVALA DGGPLTALLV LAAVIAVQQL
EGHILQPVIM RRAVSLHPIV ILVALATGSA MLGIVGAFLS VPAAAVISAV GNELRLRSER
NLLSDDTRTD APPEPLGGPG KAEVPLAEVC ADGANEPTDD AADEPG
//
