ID   R5A2M0_9CLOT            Unreviewed;       398 AA.
AC   R5A2M0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=DNA polymerase III alpha subunit Gram-positive type {ECO:0000313|EMBL:CCX37068.1};
GN   ORFNames=BN452_01052 {ECO:0000313|EMBL:CCX37068.1};
OS   Clostridium sp. CAG:1013.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262769 {ECO:0000313|EMBL:CCX37068.1, ECO:0000313|Proteomes:UP000018382};
RN   [1] {ECO:0000313|EMBL:CCX37068.1, ECO:0000313|Proteomes:UP000018382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:1013 {ECO:0000313|Proteomes:UP000018382};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX37068.1}.
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DR   EMBL; CAWF010000066; CCX37068.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5A2M0; -.
DR   Proteomes; UP000018382; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 1.10.150.870; -; 1.
DR   Gene3D; 3.30.1900.20; -; 1.
DR   Gene3D; 6.10.140.1510; -; 1.
DR   Gene3D; 1.10.150.700; PolC, middle finger domain; 1.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR004805; DnaE2/DnaE/PolC.
DR   InterPro; IPR029460; DNAPol_HHH.
DR   InterPro; IPR044923; PolC_middle_finger_sf.
DR   PANTHER; PTHR32294:SF5; DNA POLYMERASE III POLC-TYPE; 1.
DR   PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
DR   Pfam; PF14579; HHH_6; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018382}.
FT   DOMAIN          62..203
FT                   /note="DNA polymerase III alpha subunit finger"
FT                   /evidence="ECO:0000259|Pfam:PF17657"
FT   DOMAIN          309..391
FT                   /note="DNA polymerase helix-hairpin-helix motif"
FT                   /evidence="ECO:0000259|Pfam:PF14579"
SQ   SEQUENCE   398 AA;  44434 MW;  DF1CFA771E9CAA56 CRC64;
     MIVIPRGMEV YDFCPVQHPA NDQKSDNITT HFDFHSIHDN VCKLDELGHI VPTTYRYVED
     YTGIPVMEVS MSDPEVMSLF ESPAALGVTE EDLGGIKTGT LTLPELGTNF VRGMLEESHP
     KKFSDLLQVS GLSHGTDVWL GNAQELIQQG TCTISDVIGT RDSIMTYLMN KGLPPKMAFK
     IMEIVRKGKA TKLLTQEHIQ AMKEHNVPQW YIDSCFKIKY MFPKAHAAAY MIAALRLGWY
     KVHRPLEYYA AYFTVRSDDF DGVTAVKGKE AVFRKMKDLD LKIKNREASQ KEEGEFESLQ
     VVNEMLARGI SVRPVDLYRS EAKKFVVEEG EIRLPFSSLA GVGEAAAFSL REARDSGGEY
     ISIDDLQARA KVSSAVIDTL REAGALAGLP ESSQTTLF
//