ID   R5A5K3_9CLOT            Unreviewed;       321 AA.
AC   R5A5K3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Sortase family protein {ECO:0000313|EMBL:CCX36974.1};
GN   ORFNames=BN452_00978 {ECO:0000313|EMBL:CCX36974.1};
OS   Clostridium sp. CAG:1013.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262769 {ECO:0000313|EMBL:CCX36974.1, ECO:0000313|Proteomes:UP000018382};
RN   [1] {ECO:0000313|EMBL:CCX36974.1, ECO:0000313|Proteomes:UP000018382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:1013 {ECO:0000313|Proteomes:UP000018382};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX36974.1}.
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DR   EMBL; CAWF010000048; CCX36974.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5A5K3; -.
DR   Proteomes; UP000018382; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05827; Sortase_C; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR042002; Sortase_C.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   NCBIfam; NF033745; class_C_sortase; 1.
DR   NCBIfam; TIGR01076; sortase_fam; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018382};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        282..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          243..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        157
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        219
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   321 AA;  36155 MW;  22EE9DE53416E5D0 CRC64;
     MRRITGILAG IFLFLGVVAL LYHPLLTWIS QHNMEREITV FDQVIESAQS QVSEEETEFS
     SAYQNLLEDM QNYNKKLYES GQSGLTDAWN YEQAAFDFTE YGLSTEVMGV LHIPAMDEEL
     PVYLGATEEN MAKGVAVLGQ TSMPVGGTNT NCVIAGHRGY NGAAFFREIE KLHPGEYVYL
     TTYWGEKTYQ VESTAIILPD DIEAILIQED RELLTLVTCH PYVEATHRYI VYCTAIDTGA
     SDNEPISGVQ TSDEVESDTA HSADWEQAGN SSSQRRIQLE QWLPFLAIPL VILSIVILIW
     PPKKKKSCQE RRQDKNEKNT P
//