ID   R5ALG1_9CLOT            Unreviewed;       621 AA.
AC   R5ALG1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=NlpC/P60 domain-containing protein {ECO:0000259|PROSITE:PS51935};
GN   ORFNames=BN454_00936 {ECO:0000313|EMBL:CCX41617.1};
OS   Clostridium sp. CAG:1024.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262770 {ECO:0000313|EMBL:CCX41617.1, ECO:0000313|Proteomes:UP000017946};
RN   [1] {ECO:0000313|EMBL:CCX41617.1, ECO:0000313|Proteomes:UP000017946}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:1024 {ECO:0000313|Proteomes:UP000017946};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX41617.1}.
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DR   EMBL; CAWJ010000108; CCX41617.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5ALG1; -.
DR   STRING; 1262770.BN454_00936; -.
DR   Proteomes; UP000017946; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 4.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   Pfam; PF01471; PG_binding_1; 4.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF47090; PGBD-like; 4.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017946};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          493..621
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   REGION          105..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          451..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   621 AA;  65685 MW;  E691053569B341D1 CRC64;
     MKKIHVKKST VRKFRRAGKQ IKRSARFAAQ SAGRGLYLGF RSLSRTLMRL PVKTIWIGVG
     AISTALVLVI VLALALPGRA PATANADAAE PWSISAMADP AADAPNIMET AGGENGGNDA
     LPAADVPDTQ TLDTPEVQTR SEGEPTAADA AVTDGAIDMT AFKELSEGDD DPLVSEIQAR
     LMELGYMDSD EPTEHYGPLT KKSVKAFQAH NGLNSDGVCG LTTYTLLVSD NAKVYVMQSG
     DEGEDVESVQ QRLYELGYIT SKSNVTGTFG EKTDEAVKEF QKANKLTNDG KVGDKTIETL
     FSEDAVGKCF RIGDKDDTIK SVQKRLKKLG YYKGDATGEY TKTTASAVKK FQAINGLVVD
     GQLGPSTKDA ILSNDAQAYV MQLGDSGSDV EKVQKQLAKL NYMRSANATG YFGEKTEDAV
     KAFQTRNKLH SDGKVGSGTY SALFSSSAKK AKSTSTGGSS SGSGSSGSGS SGSSGNSGSG
     SSGSSGNSGS SDSKGIEKMI DIAESKLGCS YVSGAKGPNN FDCSGFVYYC LRQSGVSVSY
     MTSIGWRTTS KFKRISSLKD CKRGDILVFS GTTMAKGHVG IYLGDGKMID AGSSEGCVRI
     TKTVLSGKYW PSHFLMAYRV F
//