ID R5BBU1_9BACT Unreviewed; 464 AA.
AC R5BBU1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=BN689_01022 {ECO:0000313|EMBL:CCX53005.1};
OS Alistipes sp. CAG:514.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262696 {ECO:0000313|EMBL:CCX53005.1, ECO:0000313|Proteomes:UP000018254};
RN [1] {ECO:0000313|EMBL:CCX53005.1, ECO:0000313|Proteomes:UP000018254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:514 {ECO:0000313|Proteomes:UP000018254};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX53005.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAWO010000154; CCX53005.1; -; Genomic_DNA.
DR AlphaFoldDB; R5BBU1; -.
DR STRING; 1262696.BN689_01022; -.
DR Proteomes; UP000018254; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00585; Peptidase_C1B; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR10363; BLEOMYCIN HYDROLASE; 1.
DR PANTHER; PTHR10363:SF2; BLEOMYCIN HYDROLASE; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:CCX53005.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR005700};
KW Reference proteome {ECO:0000313|Proteomes:UP000018254};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807,
KW ECO:0000256|PIRNR:PIRNR005700}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..464
FT /note="Aminopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004375794"
FT ACT_SITE 96
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 384
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 405
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 464 AA; 52695 MW; EA3F9A345D785E0D CRC64;
MKKKTLIIAA VLLALTGVTA PAQKQNPKGG ISAEMLAEIR KGYEGTASDK AIRNALNGAA
INVLAANAEN IAMIDTHFSD EVKTKGRTNQ KSSGRCWLFS GLNVLRARMI EKYDLGAFTF
SQNYVFFYDQ LEKANLFLQG VIDTKDLSFD ERQVDWLFRN PIADGGQFTG VSNLIMKYGV
VPSDVMPETY CSNNTSQMRT QIATKLREDG LKLRDASAKD CPAMKTEMLK EIYRMLVLCL
GEPPVEFEWT RYDSKGNFVS TKTYTPKSFY NEYVGADLEN NYVMVMNDPS REFNKVYEIA
YDRHVYDGQN WLYINLPIER IKEMAIASIK DNTAMYFSCD VGKFSDRQKG TLDLDNFDYG
SLFGTTFPMD KRQRVLTHAS GSSHAMTLIA VDIKDGKTVK WMVENSWGAD SGYKGNLIMT
DEWFDNYMFR LVVEKKYVPA DILRMLDQKP TLLPAWDPMF LPEE
//
