ID R5BY54_9FIRM Unreviewed; 492 AA.
AC R5BY54;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Helix-hairpin-helix DNA-binding motif class 1 domain-containing protein {ECO:0000259|SMART:SM00278};
GN ORFNames=BN499_02447 {ECO:0000313|EMBL:CCX59154.1};
OS Blautia hydrogenotrophica CAG:147.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=1263061 {ECO:0000313|EMBL:CCX59154.1, ECO:0000313|Proteomes:UP000018163};
RN [1] {ECO:0000313|EMBL:CCX59154.1, ECO:0000313|Proteomes:UP000018163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:147 {ECO:0000313|Proteomes:UP000018163};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX59154.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAWR010000163; CCX59154.1; -; Genomic_DNA.
DR RefSeq; WP_005947138.1; NZ_HF986405.1.
DR AlphaFoldDB; R5BY54; -.
DR GeneID; 85236517; -.
DR Proteomes; UP000018163; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR023874; DNA_rSAM_put.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR010994; RuvA_2-like.
DR NCBIfam; TIGR03916; rSAM_link_UDG; 1.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF9; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01102; Uncharacterised_Radical_SAM_Su; 1.
DR SMART; SM00278; HhH1; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018163};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 382..401
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
SQ SEQUENCE 492 AA; 56340 MW; AE8C8544A450B7F5 CRC64;
MEGRQEERNL AVRESMSLEE KLTILADAAK YDVACTSSGV NRRGEKGSLG NACAAGICHS
FAADGRCISL LKILLSNECV YDCKYCLNRR SNDTPRATFT PEEICRLTIE FYKRNYIEGL
FLSSGVVRTP DYTMEQMYRT LYLLRTQYRF RGYIHVKAIP GAAPELIEQT GYLADRMSVN
LELPTAEGMK KLAPNKTHDR ILRPIRQIQR GIGEYRLSLG KDPRMERHQI NRHLSGTIFA
NGGMKITGPQ SFQNPQRKRK RSFVPAGQST QMIIGATQES DYQLLATTQA LYQKFDLKRV
FFSAYIPLNE DPLLPELGTA PPLLREHRLY QADWLLRYYG FQAEELLSPQ RPNFNVLLDP
KCDWALRHLE TFPVEINRAT YEELLKVPGI GVKSAMRIIK ARQGSSLDFD GLKKIGVVLK
RAKYFITCRG RMMYSIPIEE DFLTRQLTGE DARTNWEMGH PQSYRQLSLF EDMKLQMPPT
VEDMKKSISG QI
//
