ID R5C6C5_9FIRM Unreviewed; 491 AA.
AC R5C6C5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN ORFNames=BN499_00683 {ECO:0000313|EMBL:CCX60362.1};
OS Blautia hydrogenotrophica CAG:147.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=1263061 {ECO:0000313|EMBL:CCX60362.1, ECO:0000313|Proteomes:UP000018163};
RN [1] {ECO:0000313|EMBL:CCX60362.1, ECO:0000313|Proteomes:UP000018163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:147 {ECO:0000313|Proteomes:UP000018163};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX60362.1}.
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DR EMBL; CAWR010000271; CCX60362.1; -; Genomic_DNA.
DR Proteomes; UP000018163; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018163}.
FT DOMAIN 62..151
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 156..491
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 491 AA; 54583 MW; 5AE8D47BBF054FB8 CRC64;
MRTVSEYFGS LVFDDREMRA ALTAEVYASL RKTIDEGRKL DITVANAVAF AMKDWALSKG
ATHFTHWFQP LTGITAEKHD SFIMPAPDGG VIMEFSGKEL IKGEPDASSF PNGGLRATFE
ARGYTAWDPT SYAFIKGKEL CIPTAFCSYS GHALDKKTPL LRSMEALNKQ ALRILRLFGD
KKTKCVRPFV GCEQEYFLIT KEMYDKRPDL RYTGRTLFGA KPSKGQEMDD HYFGAIKPRV
AAYMEELNEE LWKLGVLAKT EHNEVAPAQH ELAPIYTTAN IATDHNQLTM EIMQKVARKH
NLICLLHEKP FAGVNGSGKH NNWSIATDSG QNLLSPGETP YENAQFLLVL CAVIKAVDDY
QDLLRIGVAT AGNDHRLGAN EAPPAVISIF LGDELTGVLE AIETDTPYQG VKATQMKLGV
DVLPKFRRDT TDRNRTSPFA FTGNKFEFRM VGSSDSIACS NIMLNTAVAE SLKIXXVFEN
LRGQTRGRGR F
//
