ID R5C895_9FIRM Unreviewed; 397 AA.
AC R5C895;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Non-specific protein-tyrosine kinase {ECO:0000313|EMBL:CCX64105.1};
GN ORFNames=BN785_01218 {ECO:0000313|EMBL:CCX64105.1};
OS Firmicutes bacterium CAG:791.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262993 {ECO:0000313|EMBL:CCX64105.1, ECO:0000313|Proteomes:UP000018038};
RN [1] {ECO:0000313|EMBL:CCX64105.1, ECO:0000313|Proteomes:UP000018038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:791 {ECO:0000313|Proteomes:UP000018038};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CpsC/CapA family.
CC {ECO:0000256|ARBA:ARBA00006683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX64105.1}.
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DR EMBL; CAWT010000049; CCX64105.1; -; Genomic_DNA.
DR AlphaFoldDB; R5C895; -.
DR STRING; 1262993.BN785_01218; -.
DR Proteomes; UP000018038; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF02706; Wzz; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:CCX64105.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018038};
KW Transferase {ECO:0000313|EMBL:CCX64105.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000313|EMBL:CCX64105.1}.
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..134
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..378
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 44027 MW; 6A3915705383B83F CRC64;
MIQQTQADRS SDFRNAQSGA GNAAASNYYS PQSGMGSSSD DEITIDLAEL FGVLWHWIWL
ILLVALLLGS AAYAFSKFVI PEEFQSTTKI YVLDKESGSG GQSTYTDLQV GSQLTKDYAE
LITSRTVIEK VIADNHLESV YDYKAFLKKV EVNTPTDTRI VSITVTDTNP ALAQALADDI
RVEASDLIID TMQINAVNTY EEANLPTEKS APSCSKWALI GALLGALLVG GIVTLQYILD
DTIKTSEDIE QYLGLSTLAL IPLDENIGGA EKGKKKKNKN NGKRAAMQQS APLVERPNRS
RTMNPAERQN QAPAMDPTEE ERRAPAEKKP RKPSKREMKR EMSRPNPDFD EEADFGTEEF
LGEDKLHDEE DYDYDFHEEV SADENHESDD RIQKGGN
//
