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Database: UniProt
Entry: R5D1S6_9FIRM
LinkDB: R5D1S6_9FIRM
Original site: R5D1S6_9FIRM 
ID   R5D1S6_9FIRM            Unreviewed;       727 AA.
AC   R5D1S6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   10-APR-2019, entry version 21.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN457_01809 {ECO:0000313|EMBL:CCX74128.1};
OS   Dorea sp. CAG:105.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae;
OC   Dorea; environmental samples.
OX   NCBI_TaxID=1262872 {ECO:0000313|EMBL:CCX74128.1, ECO:0000313|Proteomes:UP000017921};
RN   [1] {ECO:0000313|EMBL:CCX74128.1, ECO:0000313|Proteomes:UP000017921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:105 {ECO:0000313|Proteomes:UP000017921};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCX74128.1}.
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DR   EMBL; CAWY010000043; CCX74128.1; -; Genomic_DNA.
DR   Proteomes; UP000017921; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017921};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017921};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    279    304       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    386    409       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    421    445       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    451    471       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    510    533       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    626    645       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    657    680       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    686    707       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        2    163       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   727 AA;  79203 MW;  E1DF9876C25FBF71 CRC64;
     MSVKIALAGN PNSGKTTLFN ALTGSNQFVG NWPGVTVEKK EGKLKGHKDV VIMDLPGIYS
     LSPYTLEEVV ARNYLIGERP DAIINIVDGT NIERNLYLST QIMELGIPVV MAINMMDILA
     KTGDKIHLDK LKEKLGCDVV EISALKGTGI KAAAEQAVKL ANQKSAGAPV HEFSTKAESV
     IEQVEGKLSG IVSDDQKRFF AIKLLEKDDK IQTQMKQTVD VSSEIKELED AFDDDTESII
     TNERYVYISS IIGECVTKAK KGEKLTTSDK IDSIVTNRWL ALPIFAVIMY AVYYVSISTL
     GGILTEWTND TLFGEWIIPA AQSFFEGIGC ADWLTGLIVD GIISGVGAVL GFVPQMLVLF
     FFLAILESCG YMARVAFIMD RIFRKFGLSG KSFIPILIGT GCGVPGVMAS RTIENDRDRK
     MTIMTTTFIP CGAKLPIIAL IAGALFRNAS WVAPSAYFVG IAAIICSGIM LKKTKMFAGE
     PAPFVMELPA YHMPTAGNVL RSMWERGWSF IKKAGTIITL STIVVWFLLN FGWTNGHFGM
     LNFDGLEGAA MEAAQAQCVL AKIGNLIAWI FAPLGWGNWK MAVAAITGLV AKENVVGTFG
     QLFGFAEVAE DGKEIWGTLA SSMTQIAAYS FLVFNLLCAP CFAAMGAIKR EMNNIKWFWF
     AIGYQCILAY LVSLCIYQFG TLATGGGFGI GVVVAILIVI GFLYMLFRPY KESQTLNVNI
     KTTAKAK
//
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