ID R5D4W2_9FIRM Unreviewed; 595 AA.
AC R5D4W2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Creatinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN457_01651 {ECO:0000313|EMBL:CCX73834.1};
OS Dorea sp. CAG:105.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1262872 {ECO:0000313|EMBL:CCX73834.1, ECO:0000313|Proteomes:UP000017921};
RN [1] {ECO:0000313|EMBL:CCX73834.1, ECO:0000313|Proteomes:UP000017921}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:105 {ECO:0000313|Proteomes:UP000017921};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX73834.1}.
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DR EMBL; CAWY010000030; CCX73834.1; -; Genomic_DNA.
DR AlphaFoldDB; R5D4W2; -.
DR STRING; 1262872.BN457_01651; -.
DR Proteomes; UP000017921; Unassembled WGS sequence.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017921}.
FT DOMAIN 6..137
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 307..526
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 535..595
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 595 AA; 67956 MW; 6F26F05BE3B066E5 CRC64;
MKVSERIAKL RALMAEKGID AYVVPTADFH QSEYVGEHFK ARKYITGFSG SYGTAVICQD
DAGLWTDGRY FFQATNELEG SGVRLMKMFV GDTPSVTEYL ADKIPEGGKV GFDGRVLSMD
EGKEYEDALS PKNISIDYEE DLIDQIWEDR PPLSDKPAFF LDEKYSGESS AHKLERVRKI
MKDNGATVHI IASLDDTGWL LNVRGDDIDF FPLLLSYSIV RMDGVDLYVD ETKLNDRILE
EFKKVNVTLH PYNDIYEDIK KLDASETALI DPMKMNYALY KNIPCKIAEA ANPTILMKAM
KNDVELENIK EAHIKDGIAI TKFMYWIKTR YNKEDITELS SADKLTSLRA AQEGYIRDSF
EPLCAFADHA AMMHYSPSKE TDVVLKEGAM FLNDTGGGYY EGSTDITRTF ILGSIDQDMK
KYFTAVVRAM MNLSRANFLY GCHGYNLDVL VRQPIWDLNI DFQCGSGHGV GYLGNVHEPP
TGFRWYVVPS KNEHHQLEEG MVITDEPGIY EDGKFGIRIE NEFIVRKGEL NKYGQFMHFE
TITFAPIDLD GIDPEEMTKS EREWLNNYHK DVYEKIGPHL TDEEREWLKE YTRAI
//
