ID   R5DB11_9FIRM            Unreviewed;       551 AA.
AC   R5DB11;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=TGS domain-containing protein {ECO:0000259|PROSITE:PS51880};
GN   ORFNames=BN457_01203 {ECO:0000313|EMBL:CCX73021.1};
OS   Dorea sp. CAG:105.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1262872 {ECO:0000313|EMBL:CCX73021.1, ECO:0000313|Proteomes:UP000017921};
RN   [1] {ECO:0000313|EMBL:CCX73021.1, ECO:0000313|Proteomes:UP000017921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:105 {ECO:0000313|Proteomes:UP000017921};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX73021.1}.
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DR   EMBL; CAWY010000005; CCX73021.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5DB11; -.
DR   STRING; 1262872.BN457_01203; -.
DR   Proteomes; UP000017921; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR   CDD; cd01667; TGS_ThrRS; 1.
DR   CDD; cd02028; UMPK_like; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006083; PRK/URK.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR   PANTHER; PTHR10285:SF159; PHOSPHORIBULOKINASE _ URIDINE KINASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR10285; URIDINE KINASE; 1.
DR   Pfam; PF00485; PRK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF81271; TGS-like; 1.
DR   SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017921}.
FT   DOMAIN          1..60
FT                   /note="TGS"
FT                   /evidence="ECO:0000259|PROSITE:PS51880"
SQ   SEQUENCE   551 AA;  63072 MW;  BFF146E47A213EA7 CRC64;
     MYQVKIHDEI RQYEAGTTYL EIAKEYQKEY SHDIVLVTVD GKLQELHKKV NRDCTLNFET
     TACDSGHKTY KRSMSLLLVK AIYDVAEHEN VDKVRIHYSV SKGYYCTIEG NVVLDQQFLD
     QVEARMHQMV EADLPINKKS VNTDDAIATF ARYGMHDKEK LFAYRRVSKV NIYSINEFED
     YYYGYMVPST GYLKYFKLYL YDDGFVLQMP EQKEPEIVPP FEPQNKLFHV LKESTSWGDM
     QGIETVGALN DRITKGDVRE TVLVQEALQE KKIAEIAATI AARPELKFIL IAGPSSSGKT
     TFSHRLSVQL RACGLVPHPI AVDNYFVERE ENPVDENGDF DFECLEAVDV ELFNRQLGDL
     LAGKEVVLPR FNFVTGHKEY GPDVKKLGKN DVLVIEGIHC LNPKLTQSLP DENKFKIYIS
     ALTQLNIDEH NRIPTTDGRL LRRIVRDART RGASVARTIN MWPSVRKGEE KNIFPYQEEA
     DVMFNSALIY ELAVLKPYVE ALLFGVDRKA PEYVEAKRLL KFLDYFVGIG SENVPTNSLL
     REFIGGGCFQ I
//