ID R5DS23_9FIRM Unreviewed; 817 AA.
AC R5DS23;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=SH3 domain protein {ECO:0000313|EMBL:CCX82988.1};
GN ORFNames=BN462_00806 {ECO:0000313|EMBL:CCX82988.1};
OS Ruminococcus sp. CAG:108.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262950 {ECO:0000313|EMBL:CCX82988.1, ECO:0000313|Proteomes:UP000018037};
RN [1] {ECO:0000313|EMBL:CCX82988.1, ECO:0000313|Proteomes:UP000018037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:108 {ECO:0000313|Proteomes:UP000018037};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX82988.1}.
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DR EMBL; CAXD010000069; CCX82988.1; -; Genomic_DNA.
DR AlphaFoldDB; R5DS23; -.
DR Proteomes; UP000018037; Unassembled WGS sequence.
DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 1.10.530.40; -; 1.
DR Gene3D; 2.60.40.1080; -; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR InterPro; IPR003343; Big_2.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR023347; Lysozyme_dom_sf.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR34408; FAMILY PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR34408:SF1; GLYCOSYL HYDROLASE FAMILY 19 DOMAIN-CONTAINING PROTEIN HI_1415; 1.
DR Pfam; PF02368; Big_2; 1.
DR Pfam; PF08239; SH3_3; 4.
DR SMART; SM00635; BID_2; 2.
DR SMART; SM00287; SH3b; 4.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 2.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS51781; SH3B; 4.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW Bacteriolytic enzyme {ECO:0000256|ARBA:ARBA00022638};
KW Reference proteome {ECO:0000313|Proteomes:UP000018037};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..817
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004378137"
FT DOMAIN 49..116
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 122..189
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 217..284
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 681..747
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT REGION 191..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 817 AA; 87991 MW; A1D89D9F7AE2A2CC CRC64;
MKKQKLFVRI VCIALVVLMA VSVGAVAITA FSANAAQSTE EVSASVSAGA SGYINASYVN
LRSGAGTNYS VITCMAKNTK FTFVDGKLYN SKWYKIKLKS NSKTGYVTKE YVAVSSSTTA
SSVTGYVSDD YVNLRSGAGT NYSVVGCLRK NTKLTFVSTS LYNSAWYKVK VTSTAKTGYI
KKDYVKMNSS TQPATKATQP TTKATKPVTQ PTASASTVSG YITDDYVNLR SGAGTSYSVV
ECMRVNTKVI FVSTKLYNND WYNIKLTSNS KTGYVKKDYV KMNSQTQPTT TRPTTTKPST
GSSVKLSVSS KSIFTGNRFA ITATASGSVS WSSSNTGVAT VDSRGIVTAK KAGSATITAK
SGSHSATCKI TVKSGSSVNI SNSNVNLPWQ KSMLLKSRTS GVTWSSSNTK IATVKNGVVD
TVGKGYVTIT ASTSYGAATC LIHVMPRESV RFCYASPNSA PLNSNVSFKA ITDTGRVGVY
FVVTNGSTSY KVTATSKVKD GNSYIWTGTQ KLSKSGKWSV KAYSKFKAES KYYTTAGGGE
GEVFVTSTTN KTTTACAERR ASDEVIKLIA NYEGFLSKVT ADSITTDPTL GYGKVVISGE
QFYNNITSNQ AYAYLCQTVN KGGYTTTTNS YLVNNGIKFN QRQFDALVCF AYNVGSGVFY
NDSELQSVLL NTGSSGTIKA GASGTVTGSD VNLRRGAGTN YSVVTRMNYG TKLKFVDGKR
YNTNWYKVKL SNGTTGYIHK DYVSASGGSR DLNNVNKQNL IDALLQYHHA AGSCYWGLLY
RRVDEAETFL YGDYDRDGQH NYHHFHFSCY SNPSFGI
//
