ID   R5E622_9BURK            Unreviewed;       492 AA.
AC   R5E622;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Fumarate reductase flavoprotein subunit {ECO:0000313|EMBL:CCX86704.1};
GN   ORFNames=BN548_01668 {ECO:0000313|EMBL:CCX86704.1};
OS   Parasutterella excrementihominis CAG:233.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sutterellaceae; Parasutterella.
OX   NCBI_TaxID=1263099 {ECO:0000313|EMBL:CCX86704.1, ECO:0000313|Proteomes:UP000018034};
RN   [1] {ECO:0000313|EMBL:CCX86704.1, ECO:0000313|Proteomes:UP000018034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:233 {ECO:0000313|Proteomes:UP000018034};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase 2 family.
CC       FRD/SDH subfamily. {ECO:0000256|RuleBase:RU366062}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX86704.1}.
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DR   EMBL; CAXE010000087; CCX86704.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5E622; -.
DR   Proteomes; UP000018034; Unassembled WGS sequence.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR010960; Flavocytochrome_c.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   InterPro; IPR006311; TAT_signal.
DR   NCBIfam; TIGR01813; flavo_cyto_c; 1.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PRINTS; PR00368; FADPNR.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|RuleBase:RU366062};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU366062};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU366062}; Signal {ECO:0000256|RuleBase:RU366062}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|RuleBase:RU366062"
FT   CHAIN           34..492
FT                   /evidence="ECO:0000256|RuleBase:RU366062"
FT                   /id="PRO_5022252167"
FT   DOMAIN          43..472
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   492 AA;  52307 MW;  164774A8724E59E2 CRC64;
     MTKLSRRVFL GSAPAAAAAA GIFGTFFSTA AEAAIKWDET YNVIVIGAGG AGLSAAVSAK
     EAGAKKVVVL EKMMFAGGNT IRAGGGFNAA IKADYEKAGI TDSPKLHAEQ TLAAGDGRGD
     PVLVHQLTEK APESVQWLKD HGVKFQDHIY QIYGGLYKRA RNPIGPRGGA YIKALLEVCK
     KEDIPILYNT RVVEIIREHQ LSGRVLGVKV EQKGGKTLYL RATNAVVAAA GGFAANDRLT
     AISDPRMGQL GTTNHPGATG DVLTDLIDIG AGTRGLDYIQ CIPGGVPGEK HAPNLFTHVD
     RFLFVNLDGK RFIKEDARRD VLRDAMLDQP KAIAWTIVDA DGFEQQKNSK GPENEAALKA
     GTLYYADSIE DLAKKIGVPA NNLKEAVDTY NKAVETKKDP LGRAEGVLVN KIIKAPFYAG
     RVTMKRHHTM GGVIINKDAQ VIDRRGNVIP GLYAAGEVTG GIHGTNRVGG NAMADIFTYG
     RIAGVNAAKN PA
//