ID R5EPW8_9FIRM Unreviewed; 423 AA.
AC R5EPW8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=FHA domain-containing protein {ECO:0000259|PROSITE:PS50006};
GN ORFNames=BN466_00759 {ECO:0000313|EMBL:CCX90066.1};
OS Firmicutes bacterium CAG:110.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263000 {ECO:0000313|EMBL:CCX90066.1, ECO:0000313|Proteomes:UP000018021};
RN [1] {ECO:0000313|EMBL:CCX90066.1, ECO:0000313|Proteomes:UP000018021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:110 {ECO:0000313|Proteomes:UP000018021};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX90066.1}.
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DR EMBL; CAXG010000069; CCX90066.1; -; Genomic_DNA.
DR AlphaFoldDB; R5EPW8; -.
DR Proteomes; UP000018021; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR43019:SF23; PROTEASE DO-LIKE 5, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43019; SERINE ENDOPROTEASE DEGS; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018021};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..423
FT /note="FHA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004378722"
FT TRANSMEM 273..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..397
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
SQ SEQUENCE 423 AA; 44105 MW; EDC66C158193DBE4 CRC64;
MKYVCKRLAA MVMVLICLAA MLAIPASART DLPTVISQAK EGVVKLFVVG FSPDDTPAAA
AVGSGFAVGQ KGSTPEYFVT NWHVASAYLS EYNYAFDSDH VRIWIMLDNF TISDVTGLPS
EATSVACSIV SIAESGYPDY AILRAARPVT ECKPLPIRSS ESVKQGETVV ALGCPAAVDD
LSANVGSHDI TATRGTVARH MVMSAAGNTN VLLHDAVISG GNSGGPLIDE NGNVIGLNTY
GIVDSYSCAI YSEYVTQALD QMGIPYMTAG SSISVVTIAA AAVAVAAVAV AIYFLLRNRK
SAEKYPAGGV TPGTVPGGTV PAGVYTPSFR VQLPDGRIIP VPAGKVAVGR DPNCQIRLPE
SAAAVSRRHC TLESNGEFLI LVDEGSRNGT FIHGKRVPAG TKVALKHGSS FCVGTSENRI
TVC
//
