ID R5H8J7_9FIRM Unreviewed; 885 AA.
AC R5H8J7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=FtsK/SpoIIIE family protein {ECO:0000313|EMBL:CCY25818.1};
GN ORFNames=BN469_00788 {ECO:0000313|EMBL:CCY25818.1};
OS Firmicutes bacterium CAG:114.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263001 {ECO:0000313|EMBL:CCY25818.1, ECO:0000313|Proteomes:UP000018090};
RN [1] {ECO:0000313|EMBL:CCY25818.1, ECO:0000313|Proteomes:UP000018090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:114 {ECO:0000313|Proteomes:UP000018090};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY25818.1}.
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DR EMBL; CAXW010000029; CCY25818.1; -; Genomic_DNA.
DR AlphaFoldDB; R5H8J7; -.
DR STRING; 1263001.BN469_00788; -.
DR Proteomes; UP000018090; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000018090};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 505..696
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 853..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 522..529
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 885 AA; 95664 MW; 77EED4E6106D8821 CRC64;
MASTQKKTAN TKKQTTGKKP NGTRKKPPAY VPDLMARGIG AAVCLFLALM VVLGMVGIHA
VVPDLLCRGI RGLVGYGFWL TALALFWAAG LLLLRRERRA TLRLWCLGLL PVVGGAFLHV
LLSPRQPSLG IDLASRLWND GVYGFGGGVI SGGLAVFGTM GFSRVGAGVI FALAFLALLA
GAGHLTPPKV LRALSRLREH RAQRRYEDEA YYEEEDYEDY GDPREEAQRE APLSQGGFWP
INRRKRAPDL PLDDLPAAKQ RTGTPPQEKG KKPAPAAPAA AQVLREEEEK PPLFQPESHV
KRPDEVLEEL TQEAEAPAWK LAEDAPVWQP PGEPKPPTRA QRQAAIEKEA QEVTQTIARS
LEEDAPRAYV YPSLDLLTQP SGDSARAAHE ELEGTLDRLS SVLNSFGIDG HVTGAVQGPS
VTRYEVALEQ GVRLNKLTNL SDDVALALGV SSVRIAPVPG KISVVGIEVP NKVVIPVPIR
EVLDSPAFRR HKSSVAFSVG KDIGGNYIVG DCSKLPHMLI AGTTGSGKSV CINSLLISML
YKSTPEELRL IMVDPKMVEL GGYNGIPHLL IPVVTDPKKA AGALQWAVTE MMKRYRLFAE
AGVRELSSYN QWAKGQEGVD TMPKVVIVID ELADLMLVAA KEVEESICRV AQMGRAAGMH
LVIATQRPSA DVITGLMKAN IPSRIAFAVA SSLESRIILD NTGAEKLVGK GDMLWFPLGS
GKPLRVQGCF ISDEEVAAVV DSVKQNAAAE YDDEVMAQIE QHVTESEKKG KSAGGAFPAG
EAGEEEQDEL FPAGVDVILD LGQASVSLLQ RRLKLGYARA ARLMDQMEEK GIVGPSEGSK
PRQILITKDQ WVQMQSGGDP TPPEAAPPVE EEILTFDPVP PHYEE
//
