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Database: UniProt
Entry: R5H8U8_9FIRM
LinkDB: R5H8U8_9FIRM
Original site: R5H8U8_9FIRM 
ID   R5H8U8_9FIRM            Unreviewed;       788 AA.
AC   R5H8U8;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   10-APR-2019, entry version 24.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN469_00882 {ECO:0000313|EMBL:CCY25918.1};
OS   Firmicutes bacterium CAG:114.
OC   Bacteria; Firmicutes; environmental samples.
OX   NCBI_TaxID=1263001 {ECO:0000313|EMBL:CCY25918.1, ECO:0000313|Proteomes:UP000018090};
RN   [1] {ECO:0000313|EMBL:CCY25918.1, ECO:0000313|Proteomes:UP000018090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:114 {ECO:0000313|Proteomes:UP000018090};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCY25918.1}.
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DR   EMBL; CAXW010000042; CCY25918.1; -; Genomic_DNA.
DR   Proteomes; UP000018090; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   Gene3D; 2.30.30.90; -; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF04023; FeoA; 1.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SMART; SM00899; FeoA; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018090};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018090};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    407    434       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    472    492       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    512    535       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    547    572       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    578    597       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    636    657       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    669    688       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    695    715       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    721    747       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    759    787       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN      119    280       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
FT   COILED      339    359       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   788 AA;  85970 MW;  19FFBDC06995C44F CRC64;
     MTLKDLEIGA SGVIIAVGGE GSLRQHFLDM GVIPGAEVTL MKYAPMGDPM ELRIHGYELT
     LRLADGEKVE IAPLGADRAR EEAPREAETF AETQAHPGLG EGGKYHVKGE EHPLPPGTQL
     TFALAGNQNC GKTTLFNQLT GANQHVGNFP GVTVDRKSGS IRGHGETLVT DLPGIYSLSP
     YTSEEIVSRQ FILHEHPTGI INIVDATNIE RNLYLTMQLM ELDVPMVLAL NMMDEVRGNG
     GSIHINRMEE LLGIPVVPIS AAKNEGVEEL VNHALHVAQY QERPGRTDFC DKKDHNGAVH
     RCLHGIMHLV EDHAKAAGIP LRFAASKLVE GDPLVFDALR LSQNEQEMLE HIISQMEEER
     GLDRAAAIAD MRFSFLQKLC DQTVVRPRES KEHERSRRID AFLTGKYTAI PAFVGIMALV
     FFLTFNVIGA WFQALLEGGI SWLTVWVDEA LTAWGVNAVL HSLVIDGIFN GVGSVLSFVP
     IIVTLFFFLS LLEDSGYMAR VAFVMDKLLR KIGLSGRSIV PMLIGFGCTV PGVMASRTLP
     SERDRKMTIL LTPFMSCSAK LPIYGFFTAA FFPGRGGLIM VALYFLGILV GILMALLSKR
     TIFKGEAVPF VMELPNYRMP GIQNVAHLLW DKAKDFLQRA FTVIFLATIV VWFLQTFDFQ
     LNVVADSQNS ILAVIAGAIS PLFVPLGFGD WRVSTALIAG FMAKESVVST LSVLFGSTEQ
     LLVALTPLAV ASLLVFCLLY TPCIAAIASI RRELGGKWAV GVVVGQCVIA WVCALLVRGL
     GLAMGMIG
//
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