ID R5IES7_9FIRM Unreviewed; 542 AA.
AC R5IES7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Flavin reductase {ECO:0000313|EMBL:CCY40555.1};
GN ORFNames=BN480_01693 {ECO:0000313|EMBL:CCY40555.1};
OS Firmicutes bacterium CAG:124.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263002 {ECO:0000313|EMBL:CCY40555.1, ECO:0000313|Proteomes:UP000018269};
RN [1] {ECO:0000313|EMBL:CCY40555.1, ECO:0000313|Proteomes:UP000018269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:124 {ECO:0000313|Proteomes:UP000018269};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the SsuE family. Isf subfamily.
CC {ECO:0000256|ARBA:ARBA00038292}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY40555.1}.
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DR EMBL; CAYD010000088; CCY40555.1; -; Genomic_DNA.
DR AlphaFoldDB; R5IES7; -.
DR Proteomes; UP000018269; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.360; -; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR003680; Flavodoxin_fold.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR PANTHER; PTHR43278:SF1; IRON-SULFUR FLAVOPROTEIN MJ1083; 1.
DR PANTHER; PTHR43278; NAD(P)H-DEPENDENT FMN-CONTAINING OXIDOREDUCTASE YWQN-RELATED; 1.
DR Pfam; PF02525; Flavodoxin_2; 1.
DR Pfam; PF02036; SCP2; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000018269};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 370..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..153
FT /note="Flavodoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF02525"
FT DOMAIN 270..347
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
SQ SEQUENCE 542 AA; 60034 MW; 7DC109C76DBDD4AF CRC64;
MRVLVLNGSP KGDKSNTYRL TSAFLDGLRQ TQPVEAETIE VGKLHLLPCR GCFACWSKTP
GKCVLQDDMA GVIGKILAAD VLIWSFPLYY FSIPGQLKLL IDRQLPMSLP FMTDTDSGGH
PSRYDRSGQR QVVISTCGFY TAEGNYDAVD AQVSRLCGKD GYTSVYCGQG ELFRVPALRQ
RTDAYLELVK QAGAEFARGA ILPETARALR QPLFPRAVFE QMADASWGVS REDTAAAKTP
EAGRLSPAQA FTRQMAALYD PSTWDGRDRV LEFFYTDTGE TCQIVLGKDG QRVLQSDFLP
CTTRIETPLS VWQKIGSGEL DGKQAMMEHQ YRVTGDFSVM LHWDEIFGLG AAAPQPSAEP
RKKTNMTLML LPWMAIWIAL SIHAQIGACI GLAVCALLPF AFLNYRMTVF EPCSILAVGT
ICVLTLLDAL PLTLLLPASY LLFGLMWGVT VFLPMPLTAY YSMNGYGGET ALQNPLFMHT
NRILTACWAV LYLLTPVWTW YLLQTPVSYL TGAVNSALPM LLGAFTAWFQ RWYPAHYAAS
KK
//
