ID R5J1S4_9FIRM Unreviewed; 385 AA.
AC R5J1S4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Alanine racemase {ECO:0000313|EMBL:CCY46524.1};
GN ORFNames=BN793_00794 {ECO:0000313|EMBL:CCY46524.1};
OS Firmicutes bacterium CAG:822.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263032 {ECO:0000313|EMBL:CCY46524.1, ECO:0000313|Proteomes:UP000017964};
RN [1] {ECO:0000313|EMBL:CCY46524.1, ECO:0000313|Proteomes:UP000017964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:822 {ECO:0000313|Proteomes:UP000017964};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600821-50};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY46524.1}.
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DR EMBL; CAYG010000040; CCY46524.1; -; Genomic_DNA.
DR AlphaFoldDB; R5J1S4; -.
DR STRING; 1263032.BN793_00794; -.
DR Proteomes; UP000017964; Unassembled WGS sequence.
DR GO; GO:0008784; F:alanine racemase activity; IEA:InterPro.
DR GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR CDD; cd00430; PLPDE_III_AR; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR020622; Ala_racemase_pyridoxalP-BS.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00395; ALANINE_RACEMASE; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR600821-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000017964}.
FT DOMAIN 257..375
FT /note="Alanine racemase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01005"
FT BINDING 127
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT BINDING 325
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT MOD_RES 35
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ SEQUENCE 385 AA; 44218 MW; 03313228B6DD9A06 CRC64;
MYRKTYALIN CNTLAKNIQN IKENYPYKYY IGVVKANAYG HGDYIVNSLI AGGVNYLAAS
SLEECLSIRK RNENISILCL EPIDHEYLNI CERENITITI PDYEYFKKLD LNLNLKIHLK
IDSGMNRLGF KDKNEVKEVY DTLLNHPNIK LEGIYTHLGT SGMWDNHYDH DLKKFEEITS
LIDLKNIPIV HISRSLILVT HPMPTYVTGI RLGIIMYGFP QKINKPSGLR LIKRNMYLKK
HHISDITYEN NLNLNTAFSL HTTVMTIKSV KKGEYVGYGA KYIAEEDMKI AIIPIGFADG
LIKQYENQTV KINNKKYKLI GEVGMDMTAV KIDDSVKLKD HVIIFDDAKN KSKELGISAY
QLFTSITTRV PRVYDENGKL TEIKY
//
