ID   R5JLH9_9FIRM            Unreviewed;       522 AA.
AC   R5JLH9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Pyridine nucleotide-disulfide oxidoreductase {ECO:0000313|EMBL:CCY53619.1};
GN   ORFNames=BN781_00178 {ECO:0000313|EMBL:CCY53619.1};
OS   Coprococcus sp. CAG:782.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Coprococcus.
OX   NCBI_TaxID=1262863 {ECO:0000313|EMBL:CCY53619.1, ECO:0000313|Proteomes:UP000018002};
RN   [1] {ECO:0000313|EMBL:CCY53619.1, ECO:0000313|Proteomes:UP000018002}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:782 {ECO:0000313|Proteomes:UP000018002};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY53619.1}.
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DR   EMBL; CAYJ010000039; CCY53619.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5JLH9; -.
DR   STRING; 1262863.BN781_00178; -.
DR   Proteomes; UP000018002; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR006005; Glut_synth_ssu1.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018002}.
FT   DOMAIN          23..139
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          154..503
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   522 AA;  58090 MW;  A75A11A77A1C3847 CRC64;
     MGKPTGFMEY ERKTSVEISP KERIKNFNEF HIPLSKEEQK IQAARCMDCG VPFCQAGMMI
     CGMTSGCPLN NLIPEWNDMV YNDNWEHAYS RLAKTNNFPE FTSRVCPALC EKACTCNING
     DPVSVRENER AIIENAYEQH LVPSEPPKVR TDKTVAVIGS GPSGLAVADM LNSRGHNVTV
     YERSDRPGGL LMYGIPNMKL EKWVIDRKIS YLKKRGITFI TNTEVGPGKA MKNNSVAKDD
     PMKEYLKNPN QKYVKAEDIL NRYDAVVLAC GASNPRDIKA EGRDAKGIYF AVDFLKTTTK
     SLVDSEFANN KYVNVKGKKV LVIGGGDTGN DCVGTSVREG AADVVQLEMM PKLPDTRAAN
     NPWPEWPRVC KTDYGQQEAI AVYGHDPRIY ETTVKEFIKD ENGNVKAARC VKLDWKKDSE
     TGRMNMTEIA DSEYVIECDT VLIAAGFLGC QTYVAESFGV ELNPRTNVKT EGPDKYATNV
     PKVFAAGDMH RGQSLVVWAI HEGREAAVEV DTMLMGYSNM QD
//