ID R5L079_9CLOT Unreviewed; 390 AA.
AC R5L079;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Galactokinase {ECO:0000313|EMBL:CCY66706.1};
GN ORFNames=BN753_00415 {ECO:0000313|EMBL:CCY66706.1};
OS Clostridium sp. CAG:678.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262831 {ECO:0000313|EMBL:CCY66706.1, ECO:0000313|Proteomes:UP000017959};
RN [1] {ECO:0000313|EMBL:CCY66706.1, ECO:0000313|Proteomes:UP000017959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:678 {ECO:0000313|Proteomes:UP000017959};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY66706.1}.
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DR EMBL; CAYP010000016; CCY66706.1; -; Genomic_DNA.
DR AlphaFoldDB; R5L079; -.
DR STRING; 1262831.BN753_00415; -.
DR Proteomes; UP000017959; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10457:SF6; GALACTURONOKINASE; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCY66706.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000017959};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 6..53
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 111..174
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 288..366
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 390 AA; 43600 MW; CC6D969DC7A8D009 CRC64;
MDAETLFKQK FHTAETPLKV YCPYRIAPVG AHSDYQHGLI SGFAIDEGVT LAFLPTNDGT
VKLYSANFEG AAEFSAYELA QRSYDWGDFA KAAFVSVKRK HRVEMGMIGV IHGSLPVGGL
SSSAAVLISY ICAICKINGI QLTRPELVEL ALYAEHDYLE MNVGKMDQSC EVYSKKDHLL
FLDTLTDEYK LIPQSEKMPP YAFAVIFSGK ERKLANTAFN SRVDEAKAAS FALRAFAGIP
YGSFKDSYMR DVPKEIFDEY KSKIPPAWRR RAEHFYGEFS RVQRGAKAWE NGDIAEFGRI
MFESGHSSIY NWETGSPELK TLYEIMLKCD GIYGGRFSGA GFNGSSVALV DPAKQDDVAA
FLKEQYLAVY PQYQDDFSVR FVHTANGVEL
//
