ID   R5NC23_9BACT            Unreviewed;       671 AA.
AC   R5NC23;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Alpha-glucosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN471_02664 {ECO:0000313|EMBL:CCZ01268.1};
OS   Paraprevotella clara CAG:116.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Paraprevotella.
OX   NCBI_TaxID=1263095 {ECO:0000313|EMBL:CCZ01268.1, ECO:0000313|Proteomes:UP000017958};
RN   [1] {ECO:0000313|EMBL:CCZ01268.1, ECO:0000313|Proteomes:UP000017958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:116 {ECO:0000313|Proteomes:UP000017958};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ01268.1}.
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DR   EMBL; CAZH010000048; CCZ01268.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5NC23; -.
DR   Proteomes; UP000017958; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProt.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR029483; GH97_C.
DR   InterPro; IPR019563; GH97_catalytic.
DR   InterPro; IPR029486; GH97_N.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR   PANTHER; PTHR35803:SF2; RETAINING ALPHA-GALACTOSIDASE; 1.
DR   Pfam; PF14509; GH97_C; 1.
DR   Pfam; PF14508; GH97_N; 1.
DR   Pfam; PF10566; Glyco_hydro_97; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017958}.
FT   DOMAIN          26..308
FT                   /note="Glycosyl-hydrolase 97 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14508"
FT   DOMAIN          313..570
FT                   /note="Glycosyl-hydrolase 97 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF10566"
FT   DOMAIN          572..668
FT                   /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT                   /evidence="ECO:0000259|Pfam:PF14509"
FT   REGION          504..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   671 AA;  77529 MW;  F5CF3C266B639649 CRC64;
     MAQKIMLSLA VFFCWTFALK AEEYKLSSPD KKLEVKLRVE GRTEFEVWYD KVKLVEPSVI
     GMNLSDGRYV GGDPVTSVKK DRVNRKIDVV AGKNKTLKEA YNEIVLSYGT GYDLVVRAYN
     EGWAYRFVTH WDEEIIIDSE DAVFNFAFTP TVYFPECDSN TAPEREQSGK VHQIHQGYRN
     FERLYKVYRS PGEIPAGRFS VSPVLFEYPG KPYKVVVTES DTYDYPGLYM EAAGQNAMRG
     KWAAYPKEVM DGDPSNPYRW YSNHLVISRE DYIARTGGDR TFPWRVMIVS DDDKTLLNNE
     LVYMLAEPCK IEDTSWIQPG KSAWEWWHKA VVEGVDFPVG NKHLSLQLYK YYVDWASENG
     IEYMTLDAGW KMEYIKELCD YARGKNVKIL VWTWASCPLE NPDDWIKQMH ECGVAGAKID
     FFERNDQIAM RWGREFAERL AQYRMVAIFH GCPVPVGLNR TYPNVMNYEA VRGAECNFWE
     KTITPEYHTR FPFIRSLAGP EDYTPGGMRN VTPEEFQPRD RDSIPPMNMG TRSHVLSMYV
     IFDHWIGYLC DAPSEYNKYP DILDYLSKVP SVWDKTLPLD ARLGEYIVMA KQTGKDWYVG
     GMTNWTPRSV TVDFGFLKRG KTYRAVVFKD KPESGDHPTT YACETMNVDR NTKLTLDMAR
     GGGFAIRLTE E
//