ID R5P6J9_9BACT Unreviewed; 1036 AA.
AC R5P6J9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=CzcA family heavy metal efflux pump {ECO:0000313|EMBL:CCZ09884.1};
GN ORFNames=BN783_01103 {ECO:0000313|EMBL:CCZ09884.1};
OS Odoribacter sp. CAG:788.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Odoribacteraceae;
OC Odoribacter.
OX NCBI_TaxID=1262909 {ECO:0000313|EMBL:CCZ09884.1, ECO:0000313|Proteomes:UP000018100};
RN [1] {ECO:0000313|EMBL:CCZ09884.1, ECO:0000313|Proteomes:UP000018100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:788 {ECO:0000313|Proteomes:UP000018100};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ09884.1}.
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DR EMBL; CAZK010000086; CCZ09884.1; -; Genomic_DNA.
DR AlphaFoldDB; R5P6J9; -.
DR Proteomes; UP000018100; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF4; SLR6043 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 863..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 892..910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 958..977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 997..1020
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1036 AA; 113216 MW; 0599094EA97D3461 CRC64;
MLNKIIEFSL NNRIVVLIGA VLLILAGTYT ATNMEVDVFP DLNAPTVVVM TEAKGMAPEE
VERLVTFPVE TAVNGATDVR RVRSSSTTGF SIVWVEFNWG TDIYRARQIV SEKLAVVGDV
LPSNVGKPTL GPQSSILGEL MIIGLTADTT SLQDLRTLAD WTIRPRLLST GGVAQVTVLG
GDIKEYQILL DPGKMKHYGI GLDEVIGVVK DMNQNASGGV LYEFGNEFIV RGILSTNKVE
ALQKAVIKNV NEVPIVLENI AEVRIGAKAP KLGLASDHGK EAVLMTITRQ PATSTLELTD
QLDRSLAELQ KTLPKDVKVT TDIFRQSRFI NSSIDNVQKS LYEGGIFVVI VLFLFLMNIR
TTVISLITIP LSVIVALVTL KIMGLTINTM SLGGIAIAIG SLVDDAIVDV ENVFKRLREN
RQKPEKERKS VITVVFEASK EVRMPILNST LIIVASFVPL FFLSGMEGRM LAPLGITFVI
SLFASTFVAL TLTPVLCTYL LGNSKSKTER EPYLVRKLKK GYERALEWTL LHKKIVLGGI
SVVFVLAVIM LSSFGRSFLP PFNEGSFTVS ISTLPGVSLE ESDKIGRMAE NILLSVPEIQ
TVGRKTGRAE LDEHALGVNT SEIEAPFILG KRSKDEVLAE IREKIKMISG VNIEIGAPIT
HRIDAMLSGT RANIAIKLFG TDLNKMHEIG KRIKTSIQDV KGIADLNVEQ QVERPQLRIE
PKREMLAKYG VTLPQFADMV NVMLGGEAVS QVYEGNKSFD LTLKVNDVSR ESAGRIRQLI
VDANGRKVPL ESIADVISST GPNTISRENV ARKIVVSANV SGRDLRGVVN DIQAKISNEI
DLPEGYHVEY GGQFESEQAA SRIILIASIF SIVIIFLLLF KEFRNVKQSL VILLNLPLAL
IGGVISIYFT NGIMSIPAII GFISLFGIAT RNGMLLIDRY NSLRESGMSL RESIVQGSLD
RLNPILMTAL TSGLALIPLA LGGDLPGNEI QSPMAKVILG GLMSSTVLNG FIIPIMYLYL
NRHGEKRSET TELIEK
//
