ID R5PGN5_9BACT Unreviewed; 848 AA.
AC R5PGN5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=BN679_02105 {ECO:0000313|EMBL:CCZ15283.1};
OS Prevotella sp. CAG:487.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262928 {ECO:0000313|EMBL:CCZ15283.1, ECO:0000313|Proteomes:UP000018275};
RN [1] {ECO:0000313|EMBL:CCZ15283.1, ECO:0000313|Proteomes:UP000018275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:487 {ECO:0000313|Proteomes:UP000018275};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ15283.1}.
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DR EMBL; CAZM010000327; CCZ15283.1; -; Genomic_DNA.
DR AlphaFoldDB; R5PGN5; -.
DR Proteomes; UP000018275; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018275};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..848
FT /note="alpha-L-rhamnosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004400202"
FT DOMAIN 168..325
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 337..429
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 435..769
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 778..840
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 848 AA; 95276 MW; 64B32F17C1144B51 CRC64;
MSLRHILLCL SIVPLAFHAQ GLRTDDLKCE NLYAPLGIDN TAPHFSWKNY SPRNNARQTA
WEIQVGTDSV KVSLGEADLW NSGKRRSAES VMVGYEGRKL RSGMLCFWRV RTWDERSKVS
SWSDIHRFSV GLLTDKDFPG EYIGLDKSAG DVTAPILRKR FKLRGRHRVF IHVNSLGYHE
VRVNGRKVGD AVLAPAVSQL DKRSHIVTYD ITSYSREGDN EVEIWLGKGW YRESLFHAEY
EGPLVKAAVM RQNDAGWQPV AVTDSSWEGT PSGYHDFGTW QALQFGGERV DARILHNSGR
HWTKAHVVSV ANKTATPQMT EGNRIIDTLK PVSITAYDGG WLVDFGRDIT GWLRLEMPDV
PGDVTVRMEY GDWIDTTGVF TPQGEYDEYI TAGDGKDVFC NKFHHHAFRY VLVKNIRQPR
AEDLTALQIS GDYAETVSFK CSDDDINSIY QMISRTMRCL TFSGYMVNCP HLERMGYGGD
GNSSTMTVQT LCDVAPVYYN WLTAWGDAMA ADGDLPYVAP AGGGGGGPYW NSFIIKAPLR
TYLNYGDRRM LVKLYGQMKR WLGFVDRHVK DELLQPWADT DRRMWFLGDW LAPKGVDVGG
DSQLLTGNCV LSDCLNSMSL MADILGEKSD AGLFAAQRDS LNRKIHARFY HPADSTYATG
SPLDMSYPML TGVVPDSLRS AVTARLLALS RGKYKSHIAA GLVGTYIFTQ WAVDNGECQL
MYDILKKRSY PGYLYMIDHG ATTTWEYWSG ERSHIHNCYN GVGIWFTQAL GGIVPDISRP
GYRHVLISPQ KPDGIDWVSV DKETPYGTIR VSWHGTRLSV EIPVGVTATV VWQGRRHEDV
GSGKWTFL
//
