ID   R5PV99_9BACT            Unreviewed;      1188 AA.
AC   R5PV99;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=BN465_02106 {ECO:0000313|EMBL:CCZ12877.1};
OS   Prevotella sp. CAG:1092.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1262919 {ECO:0000313|EMBL:CCZ12877.1, ECO:0000313|Proteomes:UP000017987};
RN   [1] {ECO:0000313|EMBL:CCZ12877.1, ECO:0000313|Proteomes:UP000017987}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:1092 {ECO:0000313|Proteomes:UP000017987};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ12877.1}.
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DR   EMBL; CAZL010000394; CCZ12877.1; -; Genomic_DNA.
DR   STRING; 1262919.BN465_02106; -.
DR   Proteomes; UP000017987; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR033405; DUF5112.
DR   InterPro; IPR033406; DUF5113.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR   PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF17139; DUF5112; 1.
DR   Pfam; PF17140; DUF5113; 2.
DR   Pfam; PF02518; HATPase_c; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017987};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        408..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        717..736
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        894..914
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          496..717
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   COILED          453..552
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          972..1012
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1188 AA;  135763 MW;  92AB02E07AD55A6B CRC64;
     MDTLLRLVHN IKLFGCSIWL VSLWSILLFS ACSSNDSDVA DKLNTLSYAY HYRSLDSTEV
     YARKAFAASE SYNAGKAEAL NNLAFVNIAR MDYQKAAQQL DSAINITDNQ VELLVAEIQY
     MRLCQRQSHN KLFYIHQEKA KKYLDRIIED KNLLNSHQLK RLIYAQSEYY INISAYYYYV
     GLVEPSIETM KCIDPDGDIQ KDTAQYLNYL YNVGAGGIIT NADANVVANE EFNYLTQCYI
     VASQRNYPYW KAQALQAISE HLLSPSTRQI LITNYRPFLD YINTDGMDYS LLAGNLAQRS
     LNIFTEYKDV YQTAGAYRTL AGCYWEIDDY PSALICLNSA LEADTIINRA PDLVASIREQ
     LCLVYSAQND KVNSDINRNY YLDLQEQTRQ DKQLEARAYQ LDKSSKTLNA MIVAVLFMIA
     VVLFVLVYFA RKRKQKGATV DINELLLPLK KWNIENNKKL TDLDDKLEEV QEQTALVRLS
     EEKNKQRNLE QRAKLALVNS ITPFIDRIIN EINKLNSRHE SVELREERLK YISELTDEIN
     EYNNVLTRWI QMQQGRVSLR IESFSINELF DIVAKSKMSY SLKGISLCVE PSTAVVKADR
     VLTLFMINTL ADNARKFTPV GGKVTIKAEE KPDYVEVSIS DTGCGMDENK LAHVFDNKHI
     SDDGTTSAQS HGFGLLNCKG IIENYKKISR IFAVCDINAD SSVGKGSRFA FRLPKGVVRM
     IMALMVMVFG FTMPAYSVGN DKVERNNKKP TISRLNTQEQ HLNDAARFAD SAYYSNLNGT
     YAHTLACADS CMKYLNMHIY AHAKSKTDIP KMVLFTTSSA MPAEILWFHK EIESDYAVIL
     DIRNETAVAA LALHKWDLYR YNNKVYTRLF HECYADASLP HYVQTMQKAE NNKWVAIVIL
     VLLLISIPPI YYMVYYRHII YYKVCVERIH AINEILLGDG TDEDKLKCVE EFNSKTGNLG
     IAVLDNVVDQ ILATLRANAE SSEHKAEXXX XSEHKAEQLE YAHDELRQAE RENNILYVDN
     SVLDNCLSAL KHETMYFPSR IKQSIETKDC DIQVVAELVT YYKQLYSLLS AQAMRQIERP
     YKVDRDTMRY LFDLLKKLNG GCKPDYQVKE KDSVYVQLAF AMTSLNITSV QAQQLFTPLT
     LDVNFLICRQ IVRELGEVTN LRACGIVATA DNIIEITIPK AIWKNLIS
//