ID R5PX04_9BACT Unreviewed; 458 AA.
AC R5PX04;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 {ECO:0000313|EMBL:CCZ13467.1};
GN ORFNames=BN679_00660 {ECO:0000313|EMBL:CCZ13467.1};
OS Prevotella sp. CAG:487.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262928 {ECO:0000313|EMBL:CCZ13467.1, ECO:0000313|Proteomes:UP000018275};
RN [1] {ECO:0000313|EMBL:CCZ13467.1, ECO:0000313|Proteomes:UP000018275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:487 {ECO:0000313|Proteomes:UP000018275};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|RuleBase:RU000363}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ13467.1}.
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DR EMBL; CAZM010000033; CCZ13467.1; -; Genomic_DNA.
DR AlphaFoldDB; R5PX04; -.
DR Proteomes; UP000018275; Unassembled WGS sequence.
DR GO; GO:0070567; F:cytidylyltransferase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02516; CDP-ME_synthetase; 1.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR012115; CDP-ribitol_syn.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF01128; IspD; 1.
DR PIRSF; PIRSF036586; CDP-ribitol_syn; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:CCZ13467.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018275};
KW Transferase {ECO:0000313|EMBL:CCZ13467.1}.
SQ SEQUENCE 458 AA; 50948 MW; 914E73BC1BAE19B6 CRC64;
MKQNIAVILA GGVGTRLGMS TPKQFYKVAG KMVVEHTIDV FERNPRIDEI AIVSNPMLIA
DFENIVLRNK WRKVKKILKG GKERYDSSLS AIRAYGQREV NLIFHDAVRP LLSQRVLDDV
IDALGKYEAI DVAVPSADTI IEVEGDFISN IPDRSRLRRG QTPQAFDIRV IRTAYELALK
DPAFRTTDDC GVVRRYMPQT PVYVVRGEES NMKLTYKEDT YMMDKLFQLK NTEVGTAMPD
ARFFEGKVAV VFGGSYGIGS DIVRMLGERG ARVFAFSRSM GGVDIGDRQC VDSTLKRVAD
EAGRIDFVIS TAGILNKEPL AAMDYSVIES AVRTNYMGTV NVAVGAYPYL RQSGGHLIFF
TSSSYTRGRA FYSIYSSTKA AIVNFVQAVA QEWEGDGIKI NCINPERTKT PMRVSNFGTE
PDDTLLKPEK VAEATLRTLA SDYTGQVVDV RRAATDNR
//
