ID   R5QXF0_9FIRM            Unreviewed;       417 AA.
AC   R5QXF0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Capsule synthesis protein CapA domain-containing protein {ECO:0000259|SMART:SM00854};
GN   ORFNames=BN747_02155 {ECO:0000313|EMBL:CCZ33600.1};
OS   Firmicutes bacterium CAG:646.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262995 {ECO:0000313|EMBL:CCZ33600.1, ECO:0000313|Proteomes:UP000018386};
RN   [1] {ECO:0000313|EMBL:CCZ33600.1, ECO:0000313|Proteomes:UP000018386}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:646 {ECO:0000313|Proteomes:UP000018386};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CapA family.
CC       {ECO:0000256|ARBA:ARBA00005662}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ33600.1}.
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DR   EMBL; CAZW010000074; CCZ33600.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5QXF0; -.
DR   STRING; 1262995.BN747_02155; -.
DR   Proteomes; UP000018386; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07381; MPP_CapA; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR019079; Capsule_synth_CapA.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR33393:SF12; LIPOPROTEIN-RELATED; 1.
DR   PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   Pfam; PF09587; PGA_cap; 1.
DR   SMART; SM00854; PGA_cap; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018386};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          76..324
FT                   /note="Capsule synthesis protein CapA"
FT                   /evidence="ECO:0000259|SMART:SM00854"
SQ   SEQUENCE   417 AA;  46942 MW;  18CECE00960DAFBF CRC64;
     MEEEKAKERE QKRKRLEEQR KRQVFREKIG LVGGTVLIVL LILLALAAKG CKGKEQKAPE
     DTSLAFEVIE EPKKVTLVAA GDNLYHMPLV ETGQGESGEW NYDSIYAQVK GVIQEADLAV
     VNQETIFVKD RNNVSGYPAF GTPTEVGDAL VNLGFDVIQH ASNHAYDKQA QGVEESLQFW
     KEKHPEITVL GIHGSQEERD KITVVEKNGI KIAMLNYTYS LNGHALPESK PYLIDVWDDE
     TVREDIRKAK ELSDCIICFL HAGEEYSTEP SEDMEAKVQL LLEEGVDVMI GTHPHVLQKY
     EMKTDDAGHK MLTYYSLGNF VSTQQRPEAL LGGIAKLTLE KSEDGEVKVL DDYTLIPVVM
     QYDSDPKARA VYLLSDYTEE MAQKHRVHSY TEQEFSLSWL QETAAKIMKK DTGGDGE
//