ID   R5R1K5_9FIRM            Unreviewed;       465 AA.
AC   R5R1K5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=M18 family aminopeptidase {ECO:0000256|RuleBase:RU004387};
DE            EC=3.4.11.- {ECO:0000256|RuleBase:RU004387};
GN   ORFNames=BN734_00773 {ECO:0000313|EMBL:CCZ26897.1};
OS   [Ruminococcus] torques CAG:61.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Mediterraneibacter.
OX   NCBI_TaxID=1263108 {ECO:0000313|EMBL:CCZ26897.1, ECO:0000313|Proteomes:UP000017998};
RN   [1] {ECO:0000313|EMBL:CCZ26897.1, ECO:0000313|Proteomes:UP000017998}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:61 {ECO:0000313|Proteomes:UP000017998};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU004387};
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|RuleBase:RU004386}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ26897.1}.
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DR   EMBL; CAZS010000142; CCZ26897.1; -; Genomic_DNA.
DR   RefSeq; WP_004845396.1; NZ_HF995127.1.
DR   AlphaFoldDB; R5R1K5; -.
DR   GeneID; 60882367; -.
DR   Proteomes; UP000017998; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023358; Peptidase_M18_dom2.
DR   PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR28570:SF2; M18 FAMILY AMINOPEPTIDASE 1-RELATED; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
DR   SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000256|RuleBase:RU004386};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004386};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017998};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004386}.
SQ   SEQUENCE   465 AA;  51799 MW;  512B7CAFDE214C99 CRC64;
     MERKNIWNLY SDEQISELKE INDKYKRCLD AGKTERECVE LSVNMARDAG YRDLEEILRS
     GETLKAGDKV YAVNMNKMLA LFRIGERPIS EGMNILGAHI DSPRIDVKQN PLYENEELAY
     LDTHYYGGIK KYQWVAQPLA LHGVIVKKNG ETVKVSIGED ENDPVFVITD LLVHLAQEQL
     EKKASQVIEG EKLDLLIGNR PIEKADDLKK EEKDAVKQNV LNILKEMYGI DEEDFYSAEL
     EIVPAGKARD CGLDRSMNLS YGQDDRVCAF TSLFAMLDVT EAKKTGCCLL VDKEEIGSVG
     ATGMHSRFFE NTVAELIAVT EGESELKVRR ALSNSKMLSS DVSAAFDPMF AEAFEKRSSA
     FFANGITFNK FTGSRGKSGS NDANGEYIAA LRRTMDEAQV AYQFAELGRV DLGGGGTIAY
     IMANYGMEVI DSGVAVLNMH APYEVSSKAD VYEAVKGYRA FLRME
//