ID   R5RQK0_9CLOT            Unreviewed;       612 AA.
AC   R5RQK0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=RND family efflux transporter MFP subunit {ECO:0000313|EMBL:CCZ42943.1};
GN   ORFNames=BN479_00492 {ECO:0000313|EMBL:CCZ42943.1};
OS   Clostridium sp. CAG:122.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262773 {ECO:0000313|EMBL:CCZ42943.1, ECO:0000313|Proteomes:UP000017991};
RN   [1] {ECO:0000313|EMBL:CCZ42943.1, ECO:0000313|Proteomes:UP000017991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:122 {ECO:0000313|Proteomes:UP000017991};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ42943.1}.
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DR   EMBL; CAZY010000314; CCZ42943.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5RQK0; -.
DR   Proteomes; UP000017991; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017991};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          421..511
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   REGION          87..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..337
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          338..372
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          402..429
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        87..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   612 AA;  64136 MW;  C94973109786B515 CRC64;
     MADKEKKQAA VKSKSNKKKI KKAIISIILI GCITVIVVFN VNNKKDDTKT ETVTKENTAK
     KGNLTVGITE SGTMEIGSIT QSYELDTSSV GTSSSSSSSG TSSSGSSSSD SSNKSDAQGM
     QNMGGAMGMA GGQSGSDSSS STTKTTSSSS GNESVSDSDL VIKKVCITSG QNVKKGDTIL
     KLTTKSVSNV RKLYKAAVSS AKLSLKEAKV DRDSDKLTAE YEYKERIAAG KSAKTTYKAT
     LQSLDSAVVT AQNNYNTAVS GIKTLPLKIK NLKKKIKKEG GSTNVYKSTS TNQNTGSNAG
     NNTGNMNGTG MGDDKNGGTS GTGTTAGSTG SQSSSNTVTI MQQQLASYQQ QLSEYKSNLK
     NLKSQLKSAK KARKTGKVSA KKTYDAAMLQ YSNAKTLYNV AMDGIDDDVK DAQETLKDAQ
     KALKTFEKYA GTGVIKAECS GTVTSVGYED GETLSTDTDI ATYMNSDAVT TSVSVAQDDI
     SEIEVGDTVN ISLSAYEGKT FHGKVTSIST TSSGTSTVSY PVVVTMTGDV SSIYAGMSAD
     VTFVTKEVKD VLYISNKAVE TEGTKSYVTK KNSDASTTKT QVKTGFSDGH NVQIESGLSE
     GDTVLIESRV SE
//