ID R5S5H6_9CLOT Unreviewed; 701 AA.
AC R5S5H6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=BN479_02139 {ECO:0000313|EMBL:CCZ42231.1};
OS Clostridium sp. CAG:122.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262773 {ECO:0000313|EMBL:CCZ42231.1, ECO:0000313|Proteomes:UP000017991};
RN [1] {ECO:0000313|EMBL:CCZ42231.1, ECO:0000313|Proteomes:UP000017991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:122 {ECO:0000313|Proteomes:UP000017991};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ42231.1}.
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DR EMBL; CAZY010000220; CCZ42231.1; -; Genomic_DNA.
DR AlphaFoldDB; R5S5H6; -.
DR Proteomes; UP000017991; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:CCZ42231.1};
KW Cilium {ECO:0000313|EMBL:CCZ42231.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:CCZ42231.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017991};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..107
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 428..689
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 701 AA; 75768 MW; EDCB606D62C2A3B3 CRC64;
MPIRMTGLTS GLDTESIVNQ LMSAQRTKQT KVENKKQKLE WKQEIWKGLN TKIYGFYKDS
LSKMKYSSNY STKKASVSDS TKLTATASTK AAAGSYKVEI NKIASAQYVT SGKLDYKDTD
GKTAKTATSS TKLSDLGMSS GTVLKLEVGD KSSALEVNDS TTIKDFVDFC SNAGLNATFD
EKQQRFFLSS KDSGEENSFK LSANGYSSDG QTIVNNLNDA VGLTNLTSDQ KKTYNSIVYG
AIASGTKISD DDKATLKSLA VSSADAEATG KATAYYRAKL EKNYTLSDKD AKAINDKYAN
DNTLTADEKK AAIEKAIAEK KKADIDAAMA TDESKAAIAG LVENGIQDVT DAGIASEDAS
QYTFVGKAER DKIANTAVEN SVDAYNNAEK KGFTTENSAL AALGLENFDG TKDVSETSKG
KGMVLTKADD TEVVYNGATL KSNNTSIEVA GVTLNLLGTT AAGESVNITV SNDTSAVYDT
IKEFITEYNS ILKTMNTYYD AASASSYEVL TDDQKKAMSD DEVDKWNTKI KDSLLRRDST
LNSLISTLKT DMMGTVTASN GKTYSLANLG ITTSSKNYSE GGLLHIKGDE DDDEFADSTN
TLMQMLEEDP DTVKEVLSGL ASNLYDSLNK KMGTTTLSSA LTFYNDKEMA SQLSDYKKEI
SDWESKLSDM EEKYYSQFSA METALAKIQS QQNTLSSYLG S
//
