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Database: UniProt
Entry: R5S5Y9_9CLOT
LinkDB: R5S5Y9_9CLOT
Original site: R5S5Y9_9CLOT 
ID   R5S5Y9_9CLOT            Unreviewed;       784 AA.
AC   R5S5Y9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   31-JUL-2019, entry version 25.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN479_02277 {ECO:0000313|EMBL:CCZ42386.1};
OS   Clostridium sp. CAG:122.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1262773 {ECO:0000313|EMBL:CCZ42386.1, ECO:0000313|Proteomes:UP000017991};
RN   [1] {ECO:0000313|EMBL:CCZ42386.1, ECO:0000313|Proteomes:UP000017991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:122 {ECO:0000313|Proteomes:UP000017991};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCZ42386.1}.
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DR   EMBL; CAZY010000237; CCZ42386.1; -; Genomic_DNA.
DR   Proteomes; UP000017991; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   Gene3D; 2.30.30.90; -; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF04023; FeoA; 1.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SMART; SM00899; FeoA; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000017991};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017991};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    408    431       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    467    491       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    511    534       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    546    571       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    577    597       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    639    656       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    668    687       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    720    746       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    758    783       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN      118    279       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
FT   REGION       80    111       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      334    358       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS     97    111       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   784 AA;  86392 MW;  47FF391762778827 CRC64;
     MNKKINLSDL KAGDSAKIIS VGGEGALRQH FLDMGLIKGT TLSLIKLAPM GDPLELQLHG
     YDLTLRLDDA KKIEVEPIVS DKTPKKSKPH KSIPHPGFGE YNEEHKKEHH NPLPDDEVLT
     FALVGNQNCG KTTLFNRLTG SNQHVGNFPG VTVDRKDGVI KDHKNTLITD LPGIYSMSPY
     TSEEIVTREF ILKDKPKGII NIVDASNIER NLYLTMQLLE LNIPMVIALN MMDEVRENGG
     AIHINEMEKQ LGVPVIPISA AKNEGIEELI DHALHVTKYQ ETPIRTDFCS PDDNGSAVHA
     CIHGIMHLIE DKAKKAYIPV RFAASKLAEG DSLIKEALNL NEKESNILEQ IIQQMEEDRM
     LDRAEAIADM RFHFILKTCD GTVVKPHESK EHTRSRKIDK VLTGKYTALP SFAIIMALVF
     YLTFNVIGAA LSNLLELGIE FLTNAVDKAL TSLNVNSVLH SLVIDGIFNG VGSVLSFLPI
     IVTLFLFLSL LEDSGYMARV AFIMDKLLRK IGLSGRSIVP MLIGFGCTVP GVMASRTLSS
     ERDRKMTILL TPFMSCSAKL PIYAFFATAF FPGNAALVMI LLYFIGIIFA ITAALIFRRT
     LFKGEPVPFV MELPNYRMPG IKNVAQLLWE KAKDFLQKAF TIIFLATIVI WILQNFDFRF
     NVVEDSKSSI LASIAGVIAP VFSPAGFGDW RICTALICGF MAKESVVSTL SVLIPKTSFL
     LGIISPVNAM ALLVFCLLYT PCVAAIASIK RELGGKWALL VILLQCSIAW VAAVVVNLVG
     GIIL
//
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