ID R5S5Y9_9CLOT Unreviewed; 784 AA.
AC R5S5Y9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 31-JUL-2019, entry version 25.
DE RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN ORFNames=BN479_02277 {ECO:0000313|EMBL:CCZ42386.1};
OS Clostridium sp. CAG:122.
OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC Clostridium; environmental samples.
OX NCBI_TaxID=1262773 {ECO:0000313|EMBL:CCZ42386.1, ECO:0000313|Proteomes:UP000017991};
RN [1] {ECO:0000313|EMBL:CCZ42386.1, ECO:0000313|Proteomes:UP000017991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:122 {ECO:0000313|Proteomes:UP000017991};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units
RT of genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC system. {ECO:0000256|RuleBase:RU362098}.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data. {ECO:0000313|EMBL:CCZ42386.1}.
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DR EMBL; CAZY010000237; CCZ42386.1; -; Genomic_DNA.
DR Proteomes; UP000017991; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR CDD; cd01879; FeoB; 1.
DR Gene3D; 2.30.30.90; -; 1.
DR InterPro; IPR007167; Fe-transptr_FeoA.
DR InterPro; IPR003373; Fe2_transport_prot-B.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR038157; FeoA_core_dom.
DR InterPro; IPR041069; FeoB_Cyto.
DR InterPro; IPR030389; G_FEOB_dom.
DR InterPro; IPR011642; Gate_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR Pfam; PF04023; FeoA; 1.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF17910; FeoB_Cyto; 1.
DR Pfam; PF02421; FeoB_N; 1.
DR Pfam; PF07670; Gate; 2.
DR SMART; SM00899; FeoA; 1.
DR SUPFAM; SSF50037; SSF50037; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00437; feoB; 1.
DR PROSITE; PS51711; G_FEOB; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000017991};
KW GTP-binding {ECO:0000256|RuleBase:RU362098};
KW Ion transport {ECO:0000256|RuleBase:RU362098};
KW Iron {ECO:0000256|RuleBase:RU362098};
KW Iron transport {ECO:0000256|RuleBase:RU362098};
KW Membrane {ECO:0000256|RuleBase:RU362098};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW Reference proteome {ECO:0000313|Proteomes:UP000017991};
KW Transmembrane {ECO:0000256|RuleBase:RU362098};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW Transport {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 408 431 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 467 491 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 511 534 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 546 571 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 577 597 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 639 656 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 668 687 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 720 746 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 758 783 Helical. {ECO:0000256|RuleBase:RU362098}.
FT DOMAIN 118 279 FeoB-type G. {ECO:0000259|PROSITE:
FT PS51711}.
FT REGION 80 111 Disordered. {ECO:0000256|SAM:MobiDB-
FT lite}.
FT COILED 334 358 {ECO:0000256|SAM:Coils}.
FT COMPBIAS 97 111 Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT lite}.
SQ SEQUENCE 784 AA; 86392 MW; 47FF391762778827 CRC64;
MNKKINLSDL KAGDSAKIIS VGGEGALRQH FLDMGLIKGT TLSLIKLAPM GDPLELQLHG
YDLTLRLDDA KKIEVEPIVS DKTPKKSKPH KSIPHPGFGE YNEEHKKEHH NPLPDDEVLT
FALVGNQNCG KTTLFNRLTG SNQHVGNFPG VTVDRKDGVI KDHKNTLITD LPGIYSMSPY
TSEEIVTREF ILKDKPKGII NIVDASNIER NLYLTMQLLE LNIPMVIALN MMDEVRENGG
AIHINEMEKQ LGVPVIPISA AKNEGIEELI DHALHVTKYQ ETPIRTDFCS PDDNGSAVHA
CIHGIMHLIE DKAKKAYIPV RFAASKLAEG DSLIKEALNL NEKESNILEQ IIQQMEEDRM
LDRAEAIADM RFHFILKTCD GTVVKPHESK EHTRSRKIDK VLTGKYTALP SFAIIMALVF
YLTFNVIGAA LSNLLELGIE FLTNAVDKAL TSLNVNSVLH SLVIDGIFNG VGSVLSFLPI
IVTLFLFLSL LEDSGYMARV AFIMDKLLRK IGLSGRSIVP MLIGFGCTVP GVMASRTLSS
ERDRKMTILL TPFMSCSAKL PIYAFFATAF FPGNAALVMI LLYFIGIIFA ITAALIFRRT
LFKGEPVPFV MELPNYRMPG IKNVAQLLWE KAKDFLQKAF TIIFLATIVI WILQNFDFRF
NVVEDSKSSI LASIAGVIAP VFSPAGFGDW RICTALICGF MAKESVVSTL SVLIPKTSFL
LGIISPVNAM ALLVFCLLYT PCVAAIASIK RELGGKWALL VILLQCSIAW VAAVVVNLVG
GIIL
//
