ID R5SIT5_9FIRM Unreviewed; 419 AA.
AC R5SIT5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BN483_00280 {ECO:0000313|EMBL:CCZ46626.1};
OS Firmicutes bacterium CAG:129.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263003 {ECO:0000313|EMBL:CCZ46626.1, ECO:0000313|Proteomes:UP000018410};
RN [1] {ECO:0000313|EMBL:CCZ46626.1, ECO:0000313|Proteomes:UP000018410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:129 {ECO:0000313|Proteomes:UP000018410};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ46626.1}.
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DR EMBL; CBAB010000239; CCZ46626.1; -; Genomic_DNA.
DR AlphaFoldDB; R5SIT5; -.
DR Proteomes; UP000018410; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:CCZ46626.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018410}.
FT DOMAIN 159..419
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
SQ SEQUENCE 419 AA; 45395 MW; E1FC0A16737A8436 CRC64;
MNSIMNEYGV IGSLLIDSSL FPEAAGLPDD MFSSVPLQEI FRAMRRQYEE SGSFDALTIR
AEAGRNCTDV TDKLLTGLID TTPTTANLDA YISAVKEAAL ARFLRKIGDE LMNAEHGPTD
ALGRAQEALQ RLTEENTQGD SQTLTAALTQ LGYRVSEQVG GRAPCVASGL LRFDKLLGGG
FINSGLHVIG ARPAIGKSAL ALQIALNAAR NGVKALYLSL EMSAEDCSAR LVGNIGGLSS
ARLMFGGRLT DNEYMRFAEG TTELSALPIV FNRRSGMNVR QVEALAYREK PGLLILDHLG
LLEPPDTRLS LYEATTRNSR ALKLLALRLN VPVLCLCQLN RAAASDRSDS FRATMANLRE
SGAIEQDADT VTLLHNPPCE TDERMESPSL LELWLDKNRR GATGHVDATF YKVTGRVTA
//
