ID R5TCC0_9CLOT Unreviewed; 550 AA.
AC R5TCC0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Phospholipase D/Transphosphatidylase {ECO:0000313|EMBL:CCZ54767.1};
GN ORFNames=BN771_02126 {ECO:0000313|EMBL:CCZ54767.1};
OS Clostridium sp. CAG:75.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262836 {ECO:0000313|EMBL:CCZ54767.1, ECO:0000313|Proteomes:UP000018032};
RN [1] {ECO:0000313|EMBL:CCZ54767.1, ECO:0000313|Proteomes:UP000018032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:75 {ECO:0000313|Proteomes:UP000018032};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ54767.1}.
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DR EMBL; CBAE010000374; CCZ54767.1; -; Genomic_DNA.
DR AlphaFoldDB; R5TCC0; -.
DR Proteomes; UP000018032; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09154; PLDc_SMU_988_like_1; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000018032};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 285..312
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 464..490
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 550 AA; 64102 MW; 6B784D71F772CD88 CRC64;
MKKTPSDSSY ERWIRKQRER DADMFRRGEE HYKHLRGLKG RIQNNLSGFL RIILTAFIVL
IQFVMIIMLP LLLQNQTVYF YFILEIVAVI AMLTLINSSQ SPAYRQAWIA LALILPISGF
VMYYLWGRSS RNKKKLDQHI LRQISYGNQF LIHDEQAYQK FLQENPVAGR MVKYMETAEF
PLSAANDVKY YPMGEDAFED IFAALEQAED YILIDFFIVA EGALWDKTFE ILKRKVAQGV
EVKFLYDDFG AAIRTGKYFS TMLQKAGIDV RVFNPIHKYT GELYMNFRSH QKIVVVDGKV
AFTGGFNLAD EYANLIERFG VWKDTGVRVS GEAVWGLTIV FLQMWEASST DPEHVGYLRY
RVMPESTGDT YCHVISDGPA NNPFNPIESI YNQMIMYSDE YLYITTPYLV IEDYMKQSLI
EAAQRGVDVR IITPSIPDKK LVKILTYYNY GSLLKEGIRI YEYTPGFVHA KQILTEDAAI
VGTINMDYRS YYLHYENGIW MSGEQIQEDI RKDFCATFEE SHEVSYEEWK NRPRRYKFIE
PVLNLFSILL
//
