ID   R5TEG5_9FIRM            Unreviewed;       308 AA.
AC   R5TEG5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Tyr recombinase domain-containing protein {ECO:0000259|PROSITE:PS51898};
GN   ORFNames=BN683_01085 {ECO:0000313|EMBL:CCZ64005.1};
OS   Roseburia sp. CAG:50.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262949 {ECO:0000313|EMBL:CCZ64005.1, ECO:0000313|Proteomes:UP000018378};
RN   [1] {ECO:0000313|EMBL:CCZ64005.1, ECO:0000313|Proteomes:UP000018378}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:50 {ECO:0000313|Proteomes:UP000018378};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ64005.1}.
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DR   EMBL; CBAK010000037; CCZ64005.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5TEG5; -.
DR   Proteomes; UP000018378; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd01189; INT_ICEBs1_C_like; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR025269; SAM-like_dom.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF13102; Phage_int_SAM_5; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018378}.
FT   DOMAIN          113..300
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   308 AA;  35426 MW;  46F8DEA07EA742D7 CRC64;
     MKNDINTTEL FCDYYKQWID VYKKGAIREA TMAKYLMTQK WVERLVPELK LSELTRTAYQ
     KLLNDYAKEH ERQTTLDFHH QLKGAILDAV DEGLIKRDPT RKAIIKGKTP RVKKIKYLNQ
     FELHTLIAHL NLGETVNWDW FILLVAKTGM RFSEALAITP GDFDFARQTL SISKTWDYKG
     EGGFLPTKNK SSVRKIQIDW QIVVKFSELM KNLPEDKPIF VGDTKIYNST VNDVLTRHCK
     ECGISEISIH GLRHTHASLL LFAGVSIASV ARRLGHASMT TTQKTYLHII QELENKDVDL
     VMRTLSGL
//