ID R5TYQ2_9FIRM Unreviewed; 302 AA.
AC R5TYQ2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Cell division protein FtsX {ECO:0000256|ARBA:ARBA00021907, ECO:0000256|PIRNR:PIRNR003097};
GN ORFNames=BN683_01141 {ECO:0000313|EMBL:CCZ64061.1};
OS Roseburia sp. CAG:50.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262949 {ECO:0000313|EMBL:CCZ64061.1, ECO:0000313|Proteomes:UP000018378};
RN [1] {ECO:0000313|EMBL:CCZ64061.1, ECO:0000313|Proteomes:UP000018378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:50 {ECO:0000313|Proteomes:UP000018378};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter FtsEX involved in asymmetric
CC cellular division facilitating the initiation of sporulation.
CC {ECO:0000256|PIRNR:PIRNR003097}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR003097}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. FtsX
CC subfamily. {ECO:0000256|ARBA:ARBA00007379,
CC ECO:0000256|PIRNR:PIRNR003097}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ64061.1}.
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DR EMBL; CBAK010000040; CCZ64061.1; -; Genomic_DNA.
DR AlphaFoldDB; R5TYQ2; -.
DR Proteomes; UP000018378; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.3040; -; 1.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR004513; FtsX.
DR InterPro; IPR040690; FtsX_ECD.
DR NCBIfam; NF038347; FtsX_Gpos; 1.
DR PANTHER; PTHR47755; CELL DIVISION PROTEIN FTSX; 1.
DR PANTHER; PTHR47755:SF1; CELL DIVISION PROTEIN FTSX; 1.
DR Pfam; PF02687; FtsX; 1.
DR Pfam; PF18075; FtsX_ECD; 1.
DR PIRSF; PIRSF003097; FtsX; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR003097};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR003097};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR003097};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR003097};
KW Reference proteome {ECO:0000313|Proteomes:UP000018378};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..155
FT /note="FtsX extracellular"
FT /evidence="ECO:0000259|Pfam:PF18075"
FT DOMAIN 178..291
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
SQ SEQUENCE 302 AA; 33293 MW; 78A570BFDC31D55B CRC64;
MKISTFGYTI KQGIKNIWTN KMFSIASIAT MAACIFMFGM FYAIVANFQH VVKDVESSVA
ITVFFDEGTT QDEIDEIGQK IAMRPEVSSF NFVSADEAWA EYKLEYFDGD EAAAASFGSD
NPLSDKANYE IYMEDISQQS SLVSYLEGQD HISKVRQSEM VANTLTDFNR LVSIVSAVII
VILICVAVFL ISNTVRTGIA VRREEIGIMK MIGATDFFVR APFIVEGILI GLIGAVIPLC
ILYAMYGKII TYVASRFGFL NNLLTFLPVQ TVFEILVPVG LILGVGIGYI GSKATVHKHI
NV
//
