ID   R5URE1_9FIRM            Unreviewed;       478 AA.
AC   R5URE1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Acetyl-CoA carboxylase carboxyltransferase component (Subunits alpha and beta) {ECO:0000313|EMBL:CCZ78319.1};
GN   ORFNames=BN518_01873 {ECO:0000313|EMBL:CCZ78319.1};
OS   Roseburia sp. CAG:18.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262941 {ECO:0000313|EMBL:CCZ78319.1, ECO:0000313|Proteomes:UP000018230};
RN   [1] {ECO:0000313|EMBL:CCZ78319.1, ECO:0000313|Proteomes:UP000018230}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:18 {ECO:0000313|Proteomes:UP000018230};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ78319.1}.
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DR   EMBL; CBAP010000085; CCZ78319.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5URE1; -.
DR   Proteomes; UP000018230; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR034733; AcCoA_carboxyl_beta.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR011763; COA_CT_C.
DR   InterPro; IPR011762; COA_CT_N.
DR   PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR   PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR   Pfam; PF01039; Carboxyl_trans; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 2.
DR   PROSITE; PS50989; COA_CT_CTER; 1.
DR   PROSITE; PS50980; COA_CT_NTER; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018230};
KW   Transferase {ECO:0000313|EMBL:CCZ78319.1}.
FT   DOMAIN          1..254
FT                   /note="CoA carboxyltransferase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50980"
FT   DOMAIN          231..473
FT                   /note="CoA carboxyltransferase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50989"
SQ   SEQUENCE   478 AA;  51296 MW;  FEF105D4C4737F11 CRC64;
     MSSNNENLAI QRIAKLVDEN SFMEIGSLVT ARSTDFNLTA AKTPSDGVVI GHGLIDGNLV
     FIYSQDASVL NGTIGEMHAK KIASVYDMAM KMGAPVIGLI DCGGIRLQES VDALDGFGTI
     YAKEVAASGL VPQICGVFGN CGGGLSVVPA LCDFAFIEEK KGRMFVNAPD AIEGNNTEKC
     DTASAAFQSE NNGCVDFVGS EDEIMEQIRQ LVCMLPSNNE GDVYTDDCED DLNRACESME
     NMKGDPRYLL SQISDNNVFF ETKADYARNM VTGLIKLNGM TVGAVANCSE VYDAEGKKAE
     SFDKSLTAQG CNKAAEFVQF CDAFSIPVLT ITNVNGLKNC MCSEKKLAKA LARMTYAFSN
     ATCAKVNLIT GEAYGSAYVF MNSKSVGADL VYAWSGAKIG AMDSTLAAKI MYPEAGADEI
     KQKAADYEKL QDSAASAAAR GYVDRLIDPA DTRKYLVAAF EMLYTKYVSE PEKKHGTK
//