ID R5VED4_9FIRM Unreviewed; 875 AA.
AC R5VED4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain {ECO:0000313|EMBL:CCZ79077.1};
GN ORFNames=BN518_00383 {ECO:0000313|EMBL:CCZ79077.1};
OS Roseburia sp. CAG:18.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262941 {ECO:0000313|EMBL:CCZ79077.1, ECO:0000313|Proteomes:UP000018230};
RN [1] {ECO:0000313|EMBL:CCZ79077.1, ECO:0000313|Proteomes:UP000018230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:18 {ECO:0000313|Proteomes:UP000018230};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ79077.1}.
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DR EMBL; CBAP010000140; CCZ79077.1; -; Genomic_DNA.
DR AlphaFoldDB; R5VED4; -.
DR Proteomes; UP000018230; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000018230}.
FT DOMAIN 478..610
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 619..875
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 875 AA; 100922 MW; 9CDCD0D74C48C25D CRC64;
MNGDTNLIDI SMLQQLQDQF CCADHLYLMC VDKNKGVVTK PFGTEEQVGF LRTQVDKHAY
MELVDQMQHD RMETVVERET AQDFMKLCAV STKVEDQLQV VWIVMGIIKE RLTPEVHLPE
GMLITTEEQF YASVEFLSML SGQLFESRRN QMIAQKAVEK SSVSELAMEY QLHRSRAMTE
ILQMMDSDNS FEKVAEDILR ETCESLEISG GCLLRENVGE NTADMICEYT KEPDKSILAE
GQHIPIGALP FYNGKTYMIS SDSIMPEPFA HLFKTCHISA GIFEPIEIQN RTAMYFCVYD
NEKTRIWENR DIKFVSDVRR VVQSIMLKRI AKNSLASSYT SLEAILENTG CGIYVVDYHT
HAILYMNHQF KELFSRSIAG NHLEKMLFSD RETKRSQYYE EIYSVVEERW LDVHKTEIDW
VDGRKVAMCT LYDITEKKIY QKEIENQANN DFLTGLFNRM RCEQDLGQFI RKTREKDATG
ALLYMGLDDF KHINDGLGHQ YGDILLKAIS HSLRRIDGIE NTCYRMGGDE FVVIIPDSVY
PELERIVREV TSIFKKPWFL KGEDYYCTIS MGIVYFPKDG ETVEELVRKA DIALLSAKRR
GKNRVEYYDG MDASSSYRRL DLEKNMRTAA MNACTEFEVF YQPIIDVCQP GEPCCGAEAL
IRWNSSALGF VNPADFIPLA EYLGLINPIG EYVMRNAALR CKYWNDMGHP EYHVNVNLSV
VQLLQNDIVK KVAKVLEETR IIPQNLTLEV TERLAINDMV RMKKILSEIR NLGVRVALDD
FGTGYSSLNH IREMPLDVIK IDRCFIEHLG EDDFSNAFVR MVSELANAIN VRVCVEGVET
KRQRDIVKKM GIRMIQGFFY GKPMTIEEFE NKYLI
//
