ID R5W4Q4_9BACT Unreviewed; 871 AA.
AC R5W4Q4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN505_01193 {ECO:0000313|EMBL:CCZ98198.1};
OS Alistipes sp. CAG:157.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262692 {ECO:0000313|EMBL:CCZ98198.1, ECO:0000313|Proteomes:UP000018346};
RN [1] {ECO:0000313|EMBL:CCZ98198.1, ECO:0000313|Proteomes:UP000018346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:157 {ECO:0000313|Proteomes:UP000018346};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ98198.1}.
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DR EMBL; CBAZ010000028; CCZ98198.1; -; Genomic_DNA.
DR AlphaFoldDB; R5W4Q4; -.
DR Proteomes; UP000018346; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR032304; Peptidase_S8_N.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16361; Peptidase_S8_N; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000018346};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..39
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 40..871
FT /note="Fibronectin type-III domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004396035"
FT DOMAIN 63..204
FT /note="Subtilase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16361"
FT DOMAIN 236..524
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 243
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 298
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 485
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 871 AA; 92907 MW; B696E6953D8B3493 CRC64;
MRVSCLRRTF INQPYYRMKR YLNLLFLAAA ALCASCARDA VVSDVPPKGE DVGGYDNNVI
VPGWVRIRLD DEAAPLRTGV FTRGEADSGN PLLDELAAGL GATEIREVFP TDPRFEERHR
KYGLHLWFDI RLGDEVPVSR AEQEFAALPG VRHAQPIYRI VALDGADYPL PSEVSEPSSW
EGSSREMPFN DPGLKMQWHY DNDGTMTNAE GETVAVEGAD IGLFEAWEIY GAGDPSVIVA
VMDTGVFSGH EDLQGNMWVN EAELNGTAGK DDDGNGYRDD IHGYDFYKKS PDVEPGEHGT
HVAGTIAAVN DNGIGVSGVA GGTGNGDGVR IMTCAIYDYM GYGTATPTGY VYAADNGAVI
SQNSWNYPMI NILPEDMSVA FDYFIDNAGI GPDGEQTGPM KGGVIIFAAG NEFSPKVGCP
SDDPRVITVT SMMADYVKAS YSNYGTEADI FAPGGAGERD AAFPQQGQVY STGLDNTYTY
HSGTSMACPH VSGVAALIVS HYGANASGFT NEELKTILLR SYRNVDMWQT RPDIAAGLGA
GLVDASLMEL ENPGVPPEAP AGLEVAEGTV EERLTVSVTG LPADGNGMGI AYVNLRYAPE
EARAESGAWT SVTIPCRMSP GEALEYEVSG LADATTYVFE AGAIDRFGNE SGYVGGEGRT
IDHINRPPAI QKPLPGVELP DAAGEEPFVT AVELSDYFTD PDLPADELSY AARSNDESVA
TVSVSGSMLT VEGLKLGATY VSVTVTDLAG ESIVKNMSVK VLEERFPEDP PTPIPPEEGV
ELTEGALTLF PNPAPDALFI GVGGEAGKRA DIRVYDSAAR EVVRLDGAAF GSEGELKDVI
RYDVSGLVPG SYTVRVKLAD GRELRSTFVK A
//
