ID   R5X8U3_9FIRM            Unreviewed;       286 AA.
AC   R5X8U3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=S-adenosylmethionine-dependent methyltransferase domain-containing protein {ECO:0000259|Pfam:PF10672};
GN   ORFNames=BN568_01358 {ECO:0000313|EMBL:CDA04791.1};
OS   Blautia sp. CAG:257.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX   NCBI_TaxID=1262756 {ECO:0000313|EMBL:CDA04791.1, ECO:0000313|Proteomes:UP000018056};
RN   [1] {ECO:0000313|EMBL:CDA04791.1, ECO:0000313|Proteomes:UP000018056}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:257 {ECO:0000313|Proteomes:UP000018056};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA04791.1}.
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DR   EMBL; CBBB010000028; CDA04791.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5X8U3; -.
DR   Proteomes; UP000018056; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR019614; SAM-dep_methyl-trfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43042:SF2; SAM-DEPENDENT METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF10672; Methyltrans_SAM; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018056};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          55..200
FT                   /note="S-adenosylmethionine-dependent methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF10672"
SQ   SEQUENCE   286 AA;  32186 MW;  AE471F82D2ACE125 CRC64;
     MWIADQWKEY EVIDTSGGEK LERWGKYILV RPDPQVIWDT PKVSRGWKNM NAHYHRSKKG
     GGEWEFFDLP QQWDLHYKHL TFHLKPFSFK HTGLFPEQAV NWDWFGEKIR NAGRPVKVLN
     LFAYTGGATL AAAAAGASVT HVDASKGMVT WAKENAAASG LADAPIRWLV DDCVKFVERE
     IRRGNHYDAI IMDPPSYGRG PKGEIWKIED AIHPLIRLCK KILSPDPLFF LINSYTTGLA
     PAVLTYMLAT ELKEFNGTVD SQEIGLPVTS SGLVLPCGAS GRWESV
//