ID   R5XHL2_9FIRM            Unreviewed;       418 AA.
AC   R5XHL2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=CobW/P47K family protein {ECO:0000313|EMBL:CDA11899.1};
GN   ORFNames=BN695_00241 {ECO:0000313|EMBL:CDA11899.1};
OS   Anaerotruncus sp. CAG:528.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaerotruncus.
OX   NCBI_TaxID=1262700 {ECO:0000313|EMBL:CDA11899.1, ECO:0000313|Proteomes:UP000018024};
RN   [1] {ECO:0000313|EMBL:CDA11899.1, ECO:0000313|Proteomes:UP000018024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:528 {ECO:0000313|Proteomes:UP000018024};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA11899.1}.
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DR   EMBL; CBBE010000006; CDA11899.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5XHL2; -.
DR   STRING; 1262700.BN695_00241; -.
DR   Proteomes; UP000018024; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018024}.
FT   DOMAIN          300..416
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
FT   REGION          245..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..279
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  46975 MW;  17AD2E3B67F73CFE CRC64;
     MNKKGLVPVS LLTGYLGAGK TTLLNHVLSN QKGYRVAVIV NDIGEVNIDA SLIQKGGAVT
     QKDENLVPLS NGCICCTLKV DLMKQIISLA SSGKFDYILI EASGICEPGP IAGSICMLDG
     TDPQVELPAV AYLDNITTVV DAKRMADEFG AGDSLLKKDM DEEDIENLLV QQIEYCTTII
     LNKVDEVSPE VKENVLAVIK ALQPQAKIIE TTFGNVDVDE ILNTGRFDYE KILESAGWIQ
     AMHDEGENSE DDDDHDDNEH HEHEHEHEHE HEHEHEHEHE HGHHHHHHHH DEGEAEEYGI
     GTFVYQNVKP FEKSKFEEFV FAKWPKEVIR AKGLFWIKED PETAYIFEQS GRQKTATDDG
     KWIACFPERE RKQILQMNPD IAEAWDPVYG DRINKIVFIG RKMDKAAIIA ALDACIAK
//