ID   R5YN30_9FIRM            Unreviewed;       431 AA.
AC   R5YN30;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Saccharopine dehydrogenase and related proteins {ECO:0000313|EMBL:CDA26019.1};
GN   ORFNames=BN528_00520 {ECO:0000313|EMBL:CDA26019.1};
OS   Roseburia sp. CAG:197.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262943 {ECO:0000313|EMBL:CDA26019.1, ECO:0000313|Proteomes:UP000018336};
RN   [1] {ECO:0000313|EMBL:CDA26019.1, ECO:0000313|Proteomes:UP000018336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:197 {ECO:0000313|Proteomes:UP000018336};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA26019.1}.
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DR   EMBL; CBBL010000274; CDA26019.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5YN30; -.
DR   Proteomes; UP000018336; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR43796; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR   PANTHER; PTHR43796:SF2; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018336}.
FT   DOMAIN          5..156
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          160..406
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   431 AA;  48656 MW;  2CBE36FD29F270EA CRC64;
     MSRLLIIGCG GVASVAIRKC CQNSEVFTEI MIASRTKSKC DDLKAKIEGT TTTKIETAKV
     DADNVEELKE LIQSYKPDAV LNVALPYQDL TIMDACLACG VDYIDTANYE CEDTEDPKWR
     VIYEKRCRDL GFTAYFDYSW QWAYQEKFKE AGLTAILGSG FDPGVTSVFS AYALKHYFDE
     IHTIDILDCN GGDHGYPFAT NFNPEINLRE VSANGSYWTD GHWVETEPME WRAQYNFDQV
     GEKDMYLLHH EEIESLAKNI PGIKRIRFFM TFGQSYLTHM KCLENVGMLR TDPIMVDGKE
     IVPIQVLKEL LPDPASLGPR TVGKTNIGCI FTGIKDGKEK SIYIYNVCDH QECYKEVESQ
     AISYTTGVPA MIGSMMVVTG LWKKPGVFNL EEMDPDPYME ALNKFGLPWK VVENPVPVDC
     YKTADASVHM D
//