ID   R6ASJ5_9CLOT            Unreviewed;       331 AA.
AC   R6ASJ5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Glyoxylate reductase (NADP(+)) {ECO:0000313|EMBL:CDA51729.1};
GN   ORFNames=BN491_00882 {ECO:0000313|EMBL:CDA51729.1};
OS   Clostridium sp. CAG:138.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262775 {ECO:0000313|EMBL:CDA51729.1, ECO:0000313|Proteomes:UP000017905};
RN   [1] {ECO:0000313|EMBL:CDA51729.1, ECO:0000313|Proteomes:UP000017905}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:138 {ECO:0000313|Proteomes:UP000017905};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA51729.1}.
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DR   EMBL; CBBZ010000071; CDA51729.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6ASJ5; -.
DR   STRING; 1262775.BN491_00882; -.
DR   Proteomes; UP000017905; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd05300; 2-Hacid_dh_1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017905}.
FT   DOMAIN          111..285
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   331 AA;  36041 MW;  EEEE91FDEF2D502C CRC64;
     MNIYVAMPVT QEHVNTLKAS CPEGNFKFAR VLNGADERCA KDPFELDREM IKSADVVVGN
     IPVDILPECT RLKLLQLNMA GSDAYAGKLP AGAELANASG AYGLAISEHM LGMLLMLIKK
     LDVYRDNQNK GLWRDEGNVE SIENAKVLVV GLGDIGGEFA LRCKKLGAYC IGIRRSKAVK
     PDFVNELHTL EALDNLLSDA DVVALALPNS AESRGLMNEE RLLKMKRGAI LLNVGRGNAV
     DTDALVRVLN SGRIKAGLDV TDPEPLPQGH PLWNCPGALI TPHISGYYHL KQTHDRIIEI
     AAANIRSLLD GKPILNAVDA ETGYRKPDNR F
//