ID R6AWX7_9CLOT Unreviewed; 476 AA.
AC R6AWX7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase {ECO:0000313|EMBL:CDA51101.1};
GN ORFNames=BN491_00313 {ECO:0000313|EMBL:CDA51101.1};
OS Clostridium sp. CAG:138.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262775 {ECO:0000313|EMBL:CDA51101.1, ECO:0000313|Proteomes:UP000017905};
RN [1] {ECO:0000313|EMBL:CDA51101.1, ECO:0000313|Proteomes:UP000017905}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:138 {ECO:0000313|Proteomes:UP000017905};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-
CC [citrate lyase ACP] = diphosphate + holo-[citrate lyase ACP];
CC Xref=Rhea:RHEA:16333, Rhea:RHEA-COMP:10157, Rhea:RHEA-COMP:10158,
CC ChEBI:CHEBI:29999, ChEBI:CHEBI:33019, ChEBI:CHEBI:61378,
CC ChEBI:CHEBI:82683; EC=2.7.7.61;
CC Evidence={ECO:0000256|ARBA:ARBA00000145};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-
CC 3'-dephospho-CoA + adenine; Xref=Rhea:RHEA:15117, ChEBI:CHEBI:16708,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57328, ChEBI:CHEBI:61378; EC=2.4.2.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001210};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA51101.1}.
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DR EMBL; CBBZ010000025; CDA51101.1; -; Genomic_DNA.
DR AlphaFoldDB; R6AWX7; -.
DR STRING; 1262775.BN491_00313; -.
DR Proteomes; UP000017905; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0050519; F:holo-citrate lyase synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046917; F:triphosphoribosyl-dephospho-CoA synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR GO; GO:0051191; P:prosthetic group biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.4200.10; Triphosphoribosyl-dephospho-CoA protein; 2.
DR InterPro; IPR002736; CitG.
DR InterPro; IPR005551; CitX.
DR NCBIfam; TIGR03124; citrate_citX; 1.
DR PANTHER; PTHR30201:SF2; 2-(5''-TRIPHOSPHORIBOSYL)-3'-DEPHOSPHOCOENZYME-A SYNTHASE; 1.
DR PANTHER; PTHR30201; TRIPHOSPHORIBOSYL-DEPHOSPHO-COA SYNTHASE; 1.
DR Pfam; PF01874; CitG; 1.
DR Pfam; PF03802; CitX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017905}.
SQ SEQUENCE 476 AA; 50389 MW; A98DAEC2B11CADCD CRC64;
MSRENQMNNV GVFEMAERRE KRAAEQQDML ARCGLPLVCI NMNIAGPVKR GALIDWAFFR
ALNAAANGFK GKIRGFAFTN EKTGIEAMLA VDAAAESLKK QAESIEKEFP EGRLFDIDVI
GTDGLKLSRN VPRKCLICGQ PAAACARSRT HSAEELRKAT AELLKKAAAQ HYSELAAQAL
IREVHTTPKP GLVDENNSGA NDDMDAALFE LSTEAVQPFF AQMAKIALDA VCTAASGFSG
DFSGGAAFGG SILPKGAVSS LKQTGILAEK AMLAATGGVN THRGAIFSLG LAVCAAALSA
AGAEGHLPLR ENAGERIAKL AGKLAEAFDY ERNSGSNGAI VRRKYGVGGA IEQAKAGFPL
AIVAKSLHEE YNIESNGQGS VDSWAFALLG IMAELEDNNA LKRGGDAGAR FVKQRAAFLL
SKRTMLTEAE LLDFDDELIR RGISCGGAAD MLAAAIFLSL ADEEQRGFAE LIKTTL
//
