ID   R6BGX5_9FIRM            Unreviewed;       682 AA.
AC   R6BGX5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   ORFNames=BN708_00866 {ECO:0000313|EMBL:CDA63498.1};
OS   Firmicutes bacterium CAG:56.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263031 {ECO:0000313|EMBL:CDA63498.1, ECO:0000313|Proteomes:UP000018123};
RN   [1] {ECO:0000313|EMBL:CDA63498.1, ECO:0000313|Proteomes:UP000018123}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:56 {ECO:0000313|Proteomes:UP000018123};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA63498.1}.
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DR   EMBL; CBCG010000155; CDA63498.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6BGX5; -.
DR   Proteomes; UP000018123; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000018123}.
FT   DOMAIN          197..529
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         218..225
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   682 AA;  80763 MW;  34C25CF982B6F058 CRC64;
     MDSREYLNYV LDKLQERIRK LDDAILHGQK EIENMHEYYW ENYTEMDQYG YEDFDNQQAL
     LGQVNANKEK LDLRRRFKKM LDSPFFGRVD FIYDGEEEAE TFYIGIGNFS KESGRLPLVY
     DWRAPVSSLF YDYDKGEAYY DAPAGRMEGE VLSKWQYKIR GGKMIYAFES DVKIDDEVLK
     QELGSHGDVK LKNIIKTIQK EQNAIIRNTQ DRILAIQGVA GSGKTSVALH RIAYLLYHDR
     ENLKSSNVLV LSPNGVFSDY ISHILPELGE ENIREMSFDM FAYRELRDTV SDCEDRCDQI
     EKELLDEKYA ESCRKKQSID FVLQLNEFVL GLEDRLMRFS DLKYKGMTKS ERQLTEMFYY
     RFPDIPLLER MQAVMDYMVD EYETLIGRDL GDDEIEIVRG KFMKMYRSTD LYVLYNWFLK
     EYGYETLPQV SYEKRFLKYE DVYPMLYLKY LLKSRRMDRN IRHLVIDEMQ DYSYMQYLIL
     DKMFSCKMTI LGDKAQTMEE KTRDVLSFLP RVFGRGIRKI NMNKSYRNTM EIASYANSIS
     DVSDMELFER HGKPVEEQTF SDRKAALEAV LEKLRLEEFE TAAVIEMTQE RAKKSAAYLK
     ERMEELGMDT ENRFSVVDRD STHFKKGLTV TTFYLAKGLE FDQVFALYTT QDDTPLHRQA
     RYICATRALH ELYMYEVKAS QD
//