ID   R6BS94_9FIRM            Unreviewed;       209 AA.
AC   R6BS94;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC domain-containing protein {ECO:0000259|Pfam:PF02570};
GN   ORFNames=BN708_01193 {ECO:0000313|EMBL:CDA63839.1};
OS   Firmicutes bacterium CAG:56.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263031 {ECO:0000313|EMBL:CDA63839.1, ECO:0000313|Proteomes:UP000018123};
RN   [1] {ECO:0000313|EMBL:CDA63839.1, ECO:0000313|Proteomes:UP000018123}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:56 {ECO:0000313|Proteomes:UP000018123};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004953}.
CC   -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC       {ECO:0000256|ARBA:ARBA00009774}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA63839.1}.
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DR   EMBL; CBCG010000227; CDA63839.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6BS94; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000018123; Unassembled WGS sequence.
DR   GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR   InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR   InterPro; IPR036588; CobH/CbiC_sf.
DR   PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR   PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR   Pfam; PF02570; CbiC; 1.
DR   SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE   3: Inferred from homology;
KW   Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018123}.
FT   DOMAIN          13..207
FT                   /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT                   CobH/CbiC"
FT                   /evidence="ECO:0000259|Pfam:PF02570"
SQ   SEQUENCE   209 AA;  23086 MW;  795BB1F30596E6F8 CRC64;
     MMKIELENVL PREIEKRSFE LITEELGERT FPEEQEPIIK RCIHTSADFD YADNLCFSEG
     VVEKAKEAIR NGACIVTDTQ MAKSGINKKK LAAYGGEVFC FMSDEDVAET AKKNGTTRAT
     ACMDKAAAMN RPLIFAIGNA PTALIRLYEL IEEKKLKPEL VIGVPVGFVN VVQSKELIMQ
     ADVPYIVARG RKGGSNIAAC ICNALLYNM
//