ID R6C0Q9_9CLOT Unreviewed; 479 AA.
AC R6C0Q9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Amino acid carrier protein {ECO:0000313|EMBL:CDA69025.1};
GN ORFNames=BN687_00982 {ECO:0000313|EMBL:CDA69025.1};
OS Clostridium sp. CAG:510.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262816 {ECO:0000313|EMBL:CDA69025.1, ECO:0000313|Proteomes:UP000018120};
RN [1] {ECO:0000313|EMBL:CDA69025.1, ECO:0000313|Proteomes:UP000018120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:510 {ECO:0000313|Proteomes:UP000018120};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA69025.1}.
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DR EMBL; CBCI010000085; CDA69025.1; -; Genomic_DNA.
DR AlphaFoldDB; R6C0Q9; -.
DR STRING; 1262816.BN687_00982; -.
DR Proteomes; UP000018120; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000018120};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 17..38
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 154..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 231..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 255..282
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 321..344
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 373..396
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 450..468
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 479 AA; 51330 MW; B10282E5BAE3EA34 CRC64;
MEILDNITNV LGKVSDFVWG VPLIVLILAT GLLLTIRLKG IQITKLPRAI KNLVQNERSG
DTGEVSSFGA LCTALSATIG TGNIVGVATA IAAGGPGALF WMWMAALVGT ATKYSECLLA
VKYRQVAEDG HIVGGPFYYI EKGMGEKWKW LAKLFAIFGV MVGLFGIGTF TQINGITSAA
KNFFDPNNQH MVTIFGMEYS WAVVITGILL TIAVALVLIG GLQRISKVAE VIVPFMALLY
VVTALIILIC NITKIPAAIV TIVQSAFGAR QIAGGLAGFA VVKLSMRNGI ARGIFSNESG
IGSAPIAAAA AHTDSPAQQG LISMLGTVID TLIICTMTGL VIVITGANNI EGLEGVAVTT
KAFQLGLPFP DQVASFVLMV CLIFFAFTTI LGWDYYSERC LDYLTRHNKK KVLVYRWIYI
LCVFIGPYMT VKAVWTIADI VNGLMAFPNL IALVALNGVV VAETKLYFDS LNKKPKVKK
//
