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Database: UniProt
Entry: R6C8M4_9CLOT
LinkDB: R6C8M4_9CLOT
Original site: R6C8M4_9CLOT 
ID   R6C8M4_9CLOT            Unreviewed;       670 AA.
AC   R6C8M4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   08-MAY-2019, entry version 23.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN513_01447 {ECO:0000313|EMBL:CDA61702.1};
OS   Clostridium sp. CAG:169.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1262778 {ECO:0000313|EMBL:CDA61702.1, ECO:0000313|Proteomes:UP000018302};
RN   [1] {ECO:0000313|EMBL:CDA61702.1, ECO:0000313|Proteomes:UP000018302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:169 {ECO:0000313|Proteomes:UP000018302};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDA61702.1}.
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DR   EMBL; CBCF010000119; CDA61702.1; -; Genomic_DNA.
DR   Proteomes; UP000018302; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018302};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    285    307       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    337    370       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    390    413       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    456    476       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    514    533       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    545    566       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    573    592       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    612    633       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    645    665       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        2    163       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   670 AA;  73732 MW;  A698C37C054DEEF9 CRC64;
     MSHLLALAGN QNCGKTTLFN ALTGSNQHVG NFPGVTVEKK EGSIKKYKDA VLVDLPGIYS
     LSPYTSEEVV TRDFLVKDRP DAIINIVDAT NLERNLYLTL QLMELNIPMI LALNMMDEVR
     ASGNTIHVKK LSQELGIPVI PISAAKGEGI SDLLDTVIKT LKGDKALPRL DFCKGEVHRA
     IHSIAHIIED HAQAAGYPIR FAATKLVEGD EPMFKALDLD SGDIHIIDHI VEQMEQDLGT
     DREAALADMR YSYIEQLCAQ CVVKHQETRE QLRSEKIDRL LTSKYLGIPI FLLIMMLIFW
     LTFSVLGAPL QDLLSGWIDS FTAFLEAFLV RNQVTPWLIS LLINGVCTGV GSVLSFLPII
     VLLFFFLSLL EDSGYMARVA FVMDKLLRKI GLSGRSFVPM LIGFGCSVPA IMATRTLSSD
     RDRKMTIVLT PFMSCSAKLP IYGMITAAFF PEHPAIVMVS LYVLGIVVAI LSGLLLKNTI
     FQGNSVPFVM ELPAYRLPDA KSVLLHMWEK AKDFLHKAFT IIFIASIVIW FLQSFDWRLN
     MVSDSANSIL ASVGSIIAPL FTPLGFNDWR ASTALITGFT AKESVVSTLT ILTGASSDAQ
     LSAMLTQIFT PLSAFSFLAF TILYMPCVAA FAASKRELGS MKQALLTAGY QTLVAYIVGT
     LIYQVGSLIL
//
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